Gene: ENSG00000126217 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000126217
Transcript Identifier
ENST00000375608
Gene Type
Coding gene
Location
13 : 112902203-113096685 : positive

Family Information

Homologous gene family
HOM03P005803
(15 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P019414
(5 genes in 3 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
MCF.2 cell line derived transforming sequence-like

Identifiers

Type Value
pidENSP00000364758
HGNC14576
UniprotO15068

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007266
IEA
Genome ProjectRho protein signal transduction
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043065
TAS
Genome Projectpositive regulation of apoptotic process
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0051056
TAS
Genome Projectregulation of small GTPase mediated signal transduction
GO:0097190
TAS
Genome Projectapoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005089
IEA
Genome ProjectRho guanyl-nucleotide exchange factor activity
GO:0005545
IEA
Genome Project1-phosphatidylinositol binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IDA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0030027
IEA
Genome Projectlamellipodium

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000219Dbl homology (DH) domain
IPR001251CRAL-TRIO lipid binding domain
IPR001331Guanine-nucleotide dissociation stimulator, CDC24, conserved site
IPR001452SH3 domain
IPR001849Pleckstrin homology domain
IPR002017Spectrin repeat
IPR011511Variant SH3 domain
IPR011993PH domain-like
IPR018159Spectrin/alpha-actinin

No MapMan annotations defined for this gene.