Gene: ENSG00000125798 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000125798
Transcript Identifier
ENST00000419308
Gene Type
Coding gene
Location
20 : 22581850-22584278 : negative

Family Information

Homologous gene family
HOM03P000483
(99 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P069024
(2 genes in 2 species)
specific family

Descriptions

gene_descr
forkhead box A2

Identifiers

Type Value
pidENSP00000400341
HGNC5022
UniprotQ9Y261
UniprotB0ZTD4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001705
IEA
Genome Projectectoderm formation
GO:0001708
ISS
IEA
Genome Projectcell fate specification
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IDA
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007389
IEA
Genome Projectpattern specification process
GO:0008344
ISS
IEA
Genome Projectadult locomotory behavior
GO:0009653
IBA
IEA
Genome Projectanatomical structure morphogenesis
GO:0009952
IEA
Genome Projectanterior/posterior pattern specification
GO:0009953
IEA
Genome Projectdorsal/ventral pattern formation
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0019216
IEA
Genome Projectregulation of lipid metabolic process
GO:0019218
IEA
Genome Projectregulation of steroid metabolic process
GO:0021533
IEA
Genome Projectcell differentiation in hindbrain
GO:0021904
IEA
Genome Projectdorsal/ventral neural tube patterning
GO:0023019
IEA
Genome Projectsignal transduction involved in regulation of gene expression
GO:0030324
IEA
Genome Projectlung development
GO:0032525
IEA
Genome Projectsomite rostral/caudal axis specification
GO:0045665
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045666
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0045880
IEA
Genome Projectpositive regulation of smoothened signaling pathway
GO:0045944
IDA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048468
IEA
Genome Projectcell development
GO:0048646
IEA
Genome Projectanatomical structure formation involved in morphogenesis
GO:0048665
IEA
Genome Projectneuron fate specification
GO:0060441
IEA
Genome Projectepithelial tube branching involved in lung morphogenesis
GO:0060487
IEA
Genome Projectlung epithelial cell differentiation
GO:0061448
IEA
Genome Projectconnective tissue development
GO:0071542
ISS
IEA
Genome Projectdopaminergic neuron differentiation
GO:0090009
ISS
IEA
Genome Projectprimitive streak formation
GO:0000432
ISS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter by glucose
GO:0000433
ISS
Genome Projectnegative regulation of transcription from RNA polymerase II promoter by glucose
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0010719
IMP
Genome Projectnegative regulation of epithelial to mesenchymal transition
GO:0016568
IEA
Genome Projectchromatin modification
GO:0030154
IBA
Genome Projectcell differentiation
GO:0030193
IDA
Genome Projectregulation of blood coagulation
GO:0031018
IDA
Genome Projectendocrine pancreas development
GO:0033132
ISS
Genome Projectnegative regulation of glucokinase activity
GO:0040019
ISS
Genome Projectpositive regulation of embryonic development
GO:0043433
IMP
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045893
IDA
ISS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0061178
ISS
Genome Projectregulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070741
TAS
Genome Projectresponse to interleukin-6
GO:2000049
IC
Genome Projectpositive regulation of cell-cell adhesion mediated by cadherin
GO:2000543
ISS
Genome Projectpositive regulation of gastrulation
GO:2000971
ISS
Genome Projectnegative regulation of detection of glucose

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001205
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0001228
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0008134
IEA
Genome Projecttranscription factor binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981
IBA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0044212
IMP
Genome Projecttranscription regulatory region DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001766Fork head domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR013638Fork-head N-terminal
IPR018122Fork head domain conserved site1
IPR018533Forkhead box protein, C-terminal

No MapMan annotations defined for this gene.