Gene: ENSG00000125735 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000125735
Transcript Identifier
ENST00000599359
Gene Type
Coding gene
Location
19 : 6664926-6670069 : negative

Family Information

Homologous gene family
HOM03P034778
(2 genes in 2 species)
specific family

Descriptions

gene_descr
tumor necrosis factor (ligand) superfamily, member 14

Identifiers

Type Value
pidENSP00000469049
HGNC11930
UniprotO43557

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006955
IEA
Genome Projectimmune response
GO:0007165
TAS, NAS
Genome Projectsignal transduction
GO:0008588
IDA
Genome Projectrelease of cytoplasmic sequestered NF-kappaB
GO:0010820
IEA
Genome Projectpositive regulation of T cell chemotaxis
GO:0031295
IEA
Genome ProjectT cell costimulation
GO:0042098
NAS
Genome ProjectT cell proliferation
GO:0042110
NAS
Genome ProjectT cell activation
GO:0043029
NAS
Genome ProjectT cell homeostasis
GO:0043154
IDA
Genome Projectnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045663
IEA
Genome Projectpositive regulation of myoblast differentiation
GO:0071260
IEP
Genome Projectcellular response to mechanical stimulus
GO:1901741
IEA
Genome Projectpositive regulation of myoblast fusion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IPI
TAS
Genome Projectreceptor binding
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005164
IEA
Genome Projecttumor necrosis factor receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043027
IDA
Genome Projectcysteine-type endopeptidase inhibitor activity involved in apoptotic process

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006052Tumour necrosis factor domain
IPR006053Tumour necrosis factor
IPR008983Tumour necrosis factor-like domain

No MapMan annotations defined for this gene.