Gene: ENSG00000125651 (Homo sapiens)

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Gene Identifier
ENSG00000125651
Transcript Identifier
ENST00000394456
Gene Type
Coding gene
Location
19 : 6380281-6392995 : negative

Family Information

Homologous gene family
HOM03P023275
(4 genes in 4 species)
specific family

Descriptions

gene_descr
general transcription factor IIF, polypeptide 1, 74kDa

Identifiers

Type Value
pidENSP00000377969
HGNC4652
UniprotP35269

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000398
TAS
Genome ProjectmRNA splicing, via spliceosome
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
TAS
Genome Projecttranscription from RNA polymerase II promoter
GO:0006367
TAS, IEA
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006368
TAS
Genome Projecttranscription elongation from RNA polymerase II promoter
GO:0006370
TAS
Genome Project7-methylguanosine mRNA capping
GO:0008380
TAS
Genome ProjectRNA splicing
GO:0009615
IEP
Genome Projectresponse to virus
GO:0010467
TAS
Genome Projectgene expression
GO:0016032
TAS
Genome Projectviral process
GO:0032968
IEA
Genome Projectpositive regulation of transcription elongation from RNA polymerase II promoter
GO:0043085
IDA
Genome Projectpositive regulation of catalytic activity
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0050434
TAS
Genome Projectpositive regulation of viral transcription

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003713
TAS
Genome Projecttranscription coactivator activity
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0019211
IDA
Genome Projectphosphatase activator activity
GO:0044822
IDA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005674
TAS
Genome Projecttranscription factor TFIIF complex
GO:0030054
IDA
Genome Projectcell junction

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR008851Transcription initiation factor IIF, alpha subunit
IPR011039Transcription Factor IIF, Rap30/Rap74, interaction
IPR011991Winged helix-turn-helix DNA-binding domain

No MapMan annotations defined for this gene.