Gene: ENSG00000124766 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000124766
Transcript Identifier
ENST00000244745
Gene Type
Coding gene
Location
6 : 21594535-21595959 : positive

Family Information

Homologous gene family
HOM03P001338
(53 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P062712
(2 genes in 2 species)
specific family

Descriptions

gene_descr
SRY (sex determining region Y)-box 4

Identifiers

Type Value
pidENSP00000244745
HGNC11200
UniprotQ06945

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001501
ISS
IEA
Genome Projectskeletal system development
GO:0001841
ISS
IEA
Genome Projectneural tube formation
GO:0002328
ISS
IEA
Genome Projectpro-B cell differentiation
GO:0003183
ISS
IEA
Genome Projectmitral valve morphogenesis
GO:0003211
ISS
IEA
Genome Projectcardiac ventricle formation
GO:0003215
ISS
IEA
Genome Projectcardiac right ventricle morphogenesis
GO:0003289
ISS
IEA
Genome Projectatrial septum primum morphogenesis
GO:0003357
ISS
IEA
Genome Projectnoradrenergic neuron differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006977
IMP
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007507
ISS
IEA
Genome Projectheart development
GO:0008284
IMP
Genome Projectpositive regulation of cell proliferation
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0014009
ISS
IEA
Genome Projectglial cell proliferation
GO:0021510
ISS
IEA
Genome Projectspinal cord development
GO:0021522
ISS
IEA
Genome Projectspinal cord motor neuron differentiation
GO:0021782
ISS
IEA
Genome Projectglial cell development
GO:0030177
ISS
IEA
Genome Projectpositive regulation of Wnt signaling pathway
GO:0030217
ISS
IEA
Genome ProjectT cell differentiation
GO:0031018
IEA
Genome Projectendocrine pancreas development
GO:0031397
IMP
Genome Projectnegative regulation of protein ubiquitination
GO:0031647
IMP
Genome Projectregulation of protein stability
GO:0032024
ISS
IEA
Genome Projectpositive regulation of insulin secretion
GO:0035019
IEA
Genome Projectsomatic stem cell population maintenance
GO:0035910
ISS
IEA
Genome Projectascending aorta morphogenesis
GO:0042593
ISS
IEA
Genome Projectglucose homeostasis
GO:0042769
IDA
Genome ProjectDNA damage response, detection of DNA damage
GO:0043065
IMP
Genome Projectpositive regulation of apoptotic process
GO:0045727
IMP
Genome Projectpositive regulation of translation
GO:0045893
IDA, IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046826
IMP
Genome Projectnegative regulation of protein export from nucleus
GO:0048485
ISS
IEA
Genome Projectsympathetic nervous system development
GO:0050821
IMP
Genome Projectprotein stabilization
GO:0060070
ISS
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0060174
ISS
IEA
Genome Projectlimb bud formation
GO:0060412
ISS
IEA
Genome Projectventricular septum morphogenesis
GO:0060548
ISS
IEA
Genome Projectnegative regulation of cell death
GO:0060563
ISS
IEA
Genome Projectneuroepithelial cell differentiation
GO:0060993
ISS
IEA
Genome Projectkidney morphogenesis
GO:0071333
ISS
IEA
Genome Projectcellular response to glucose stimulus
GO:0090263
ISS
IEA
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:2000761
IDA
Genome Projectpositive regulation of N-terminal peptidyl-lysine acetylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000976
ISS
IEA
Genome Projecttranscription regulatory region sequence-specific DNA binding
GO:0000981
IEA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001046
IDA
Genome Projectcore promoter sequence-specific DNA binding
GO:0001071
IMP
Genome Projectnucleic acid binding transcription factor activity
GO:0001077
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001105
ISS
IEA
Genome ProjectRNA polymerase II transcription coactivator activity
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
IDA
TAS
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005739
IDA
Genome Projectmitochondrion
GO:0044798
IEA
Genome Projectnuclear transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009071High mobility group box domain

No MapMan annotations defined for this gene.