Gene: ENSG00000123338 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000123338
Transcript Identifier
ENST00000293373
Gene Type
Coding gene
Location
12 : 54497790-54542685 : positive

Family Information

Homologous gene family
HOM03P005683
(16 genes in 13 species)
specific family

Descriptions

gene_descr
NCK-associated protein 1-like

Identifiers

Type Value
pidENSP00000293373
HGNC4862
UniprotP55160

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001782
ISS
IEA
Genome ProjectB cell homeostasis
GO:0002262
ISS
IEA
Genome Projectmyeloid cell homeostasis
GO:0006461
ISS
IEA
Genome Projectprotein complex assembly
GO:0006935
IDA
Genome Projectchemotaxis
GO:0030011
IMP
Genome Projectmaintenance of cell polarity
GO:0030593
IDA
Genome Projectneutrophil chemotaxis
GO:0030838
IMP
Genome Projectpositive regulation of actin filament polymerization
GO:0030866
IMP
Genome Projectcortical actin cytoskeleton organization
GO:0030890
IMP
Genome Projectpositive regulation of B cell proliferation
GO:0032147
IMP
Genome Projectactivation of protein kinase activity
GO:0032700
ISS
IEA
Genome Projectnegative regulation of interleukin-17 production
GO:0032715
ISS
IEA
Genome Projectnegative regulation of interleukin-6 production
GO:0033630
ISS
IEA
Genome Projectpositive regulation of cell adhesion mediated by integrin
GO:0035509
IMP
Genome Projectnegative regulation of myosin-light-chain-phosphatase activity
GO:0042102
ISS
IEA
Genome Projectpositive regulation of T cell proliferation
GO:0042327
IMP
Genome Projectpositive regulation of phosphorylation
GO:0042493
IMP
Genome Projectresponse to drug
GO:0043029
ISS
IEA
Genome ProjectT cell homeostasis
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0043372
ISS
IEA
Genome Projectpositive regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043378
ISS
IEA
Genome Projectpositive regulation of CD8-positive, alpha-beta T cell differentiation
GO:0043547
IMP
Genome Projectpositive regulation of GTPase activity
GO:0045579
ISS
IEA
Genome Projectpositive regulation of B cell differentiation
GO:0045588
ISS
IEA
Genome Projectpositive regulation of gamma-delta T cell differentiation
GO:0045621
ISS
IEA
Genome Projectpositive regulation of lymphocyte differentiation
GO:0045648
ISS
IEA
Genome Projectpositive regulation of erythrocyte differentiation
GO:0048821
IEP
Genome Projecterythrocyte development
GO:0050853
IMP
Genome ProjectB cell receptor signaling pathway
GO:0060100
ISS
IEA
Genome Projectpositive regulation of phagocytosis, engulfment
GO:0070358
IMP
Genome Projectactin polymerization-dependent cell motility
GO:0090023
ISS
IEA
Genome Projectpositive regulation of neutrophil chemotaxis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005096
IMP
Genome ProjectGTPase activator activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0030295
IMP
Genome Projectprotein kinase activator activity
GO:0032403
IDA
Genome Projectprotein complex binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005829
IDA
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005887
NAS
Genome Projectintegral component of plasma membrane
GO:0016020
IDA
TAS, IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031209
IDA
Genome ProjectSCAR complex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR019137Nck-associated protein 1

No MapMan annotations defined for this gene.