Gene: ENSG00000123268 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000123268
Transcript Identifier
ENST00000262053
Gene Type
Coding gene
Location
12 : 50780146-50819779 : positive

Family Information

Homologous gene family
HOM03P016560
(5 genes in 4 species)
specific family

Descriptions

gene_descr
activating transcription factor 1

Identifiers

Type Value
pidENSP00000262053
HGNC783
UniprotP18846

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0010976
IEA
Genome Projectpositive regulation of neuron projection development
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0032025
IEA
Genome Projectresponse to cobalt ion
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034146
TAS
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034162
TAS
Genome Projecttoll-like receptor 9 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0043623
IEA
Genome Projectcellular protein complex assembly
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045740
IEA
Genome Projectpositive regulation of DNA replication
GO:0045944
IDA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0051403
TAS
Genome Projectstress-activated MAPK cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003700
TAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005667
IEA
Genome Projecttranscription factor complex
GO:1990590
IDA
Genome ProjectATF1-ATF4 transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001630cAMP response element binding (CREB) protein
IPR003102Coactivator CBP, pKID
IPR004827Basic-leucine zipper domain
IPR029825cAMP-dependent transcription factor ATF1

No MapMan annotations defined for this gene.