Gene: ENSG00000122861 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000122861
Transcript Identifier
ENST00000372764
Gene Type
Coding gene
Location
10 : 73911556-73916565 : positive

Family Information

Homologous gene family
HOM03P000033
(649 genes in 22 species)
specific family
Orthologous gene family
ORTHO03P066612
(2 genes in 2 species)
specific family

Descriptions

gene_descr
plasminogen activator, urokinase

Identifiers

Type Value
pidENSP00000361850
HGNC9052
UniprotP00749

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0006508
TAS, IEA
Genome Projectproteolysis
GO:0006935
TAS
Genome Projectchemotaxis
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0007566
IEA
Genome Projectembryo implantation
GO:0007596
TAS, IEA
Genome Projectblood coagulation
GO:0007599
IEA
Genome Projecthemostasis
GO:0008284
IEA
Genome Projectpositive regulation of cell proliferation
GO:0010469
IDA
Genome Projectregulation of receptor activity
GO:0014823
IEA
Genome Projectresponse to activity
GO:0014909
IEA
Genome Projectsmooth muscle cell migration
GO:0014910
IDA
Genome Projectregulation of smooth muscle cell migration
GO:0014911
IEA
Genome Projectpositive regulation of smooth muscle cell migration
GO:0031639
IBA
Genome Projectplasminogen activation
GO:0033628
IDA
Genome Projectregulation of cell adhesion mediated by integrin
GO:0035728
IEA
Genome Projectresponse to hepatocyte growth factor
GO:0035729
IEA
Genome Projectcellular response to hepatocyte growth factor stimulus
GO:0042060
IEA
Genome Projectwound healing
GO:0042127
IEA
Genome Projectregulation of cell proliferation
GO:0042730
IBA
TAS, IEA
Genome Projectfibrinolysis
GO:0043403
IEA
Genome Projectskeletal muscle tissue regeneration
GO:0055093
IEA
Genome Projectresponse to hyperoxia
GO:0060279
IEA
Genome Projectpositive regulation of ovulation
GO:0061041
IC
Genome Projectregulation of wound healing
GO:0070997
IEA
Genome Projectneuron death
GO:0071222
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071310
IEA
Genome Projectcellular response to organic substance
GO:0071333
IEA
Genome Projectcellular response to glucose stimulus
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0071498
IEA
Genome Projectcellular response to fluid shear stress
GO:0072734
IEA
Genome Projectcellular response to staurosporine
GO:2000097
IDA
Genome Projectregulation of smooth muscle cell-matrix adhesion
GO:2000345
IEA
Genome Projectregulation of hepatocyte proliferation
GO:2000379
IEA
Genome Projectpositive regulation of reactive oxygen species metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004252
IBA
TAS, IEA
Genome Projectserine-type endopeptidase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0008236
IEA
Genome Projectserine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000001Kringle
IPR000742EGF-like domain
IPR001254Serine proteases, trypsin domain
IPR001314Peptidase S1A, chymotrypsin-type
IPR009003Peptidase S1, PA clan
IPR013032EGF-like, conserved site
IPR013806Kringle-like fold
IPR018056Kringle, conserved site
IPR018114Peptidase S1, trypsin family, active site

No MapMan annotations defined for this gene.