Gene: ENSG00000121897 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000121897
Transcript Identifier
ENST00000261434
Gene Type
Coding gene
Location
4 : 39459118-39477115 : positive

Family Information

Homologous gene family
HOM03P000768
(74 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P001677
(36 genes in 34 species)
specific family

Descriptions

gene_descr
lipoic acid synthetase

Identifiers

Type Value
pidENSP00000261434
HGNC16429
UniprotO43766
UniprotA0A024R9W0

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001843
IEA
Genome Projectneural tube closure
GO:0006954
ISS
IEA
Genome Projectinflammatory response
GO:0006979
ISS
IEA
Genome Projectresponse to oxidative stress
GO:0009107
ISS, IBA
IEA
Genome Projectlipoate biosynthetic process
GO:0009249
IBA
IEA
Genome Projectprotein lipoylation
GO:0032496
ISS
IEA
Genome Projectresponse to lipopolysaccharide

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016783
IEA
Genome Projectsulfurtransferase activity
GO:0016992
ISS, IBA
IEA
Genome Projectlipoate synthase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051536
IEA
Genome Projectiron-sulfur cluster binding
GO:0051539
IEA
Genome Project4 iron, 4 sulfur cluster binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
ISS, IBA
IEA
Genome Projectmitochondrion

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003698Lipoyl synthase
IPR006638Elongator protein 3/MiaB/NifB
IPR007197Radical SAM
IPR013785Aldolase-type TIM barrel
IPR031691Lipoyl synthase, N-terminal

No MapMan annotations defined for this gene.