Gene: ENSG00000121060 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000121060
Transcript Identifier
ENST00000537230
Gene Type
Coding gene
Location
17 : 56891700-56913988 : negative

Family Information

Homologous gene family
HOM03P013190
(6 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P074145
(2 genes in 2 species)
specific family

Descriptions

gene_descr
tripartite motif containing 25

Identifiers

Type Value
pidENSP00000445961
HGNC12932
UniprotQ14258

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002376
IEA
Genome Projectimmune system process
GO:0006281
TAS
Genome ProjectDNA repair
GO:0006513
IMP
Genome Projectprotein monoubiquitination
GO:0016032
IEA
Genome Projectviral process
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0019221
TAS
Genome Projectcytokine-mediated signaling pathway
GO:0019985
TAS
Genome Projecttranslesion synthesis
GO:0032480
TAS
Genome Projectnegative regulation of type I interferon production
GO:0036503
IMP
Genome ProjectERAD pathway
GO:0042787
IMP
Genome Projectprotein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043123
IDA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045087
IDA
TAS, IEA
Genome Projectinnate immune response
GO:0046596
IDA
Genome Projectregulation of viral entry into host cell
GO:0046597
IEA
Genome Projectnegative regulation of viral entry into host cell
GO:0051091
IMP
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092
IMP
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051607
IEA
Genome Projectdefense response to virus
GO:0060333
TAS
Genome Projectinterferon-gamma-mediated signaling pathway
GO:1902186
IMP
Genome Projectregulation of viral release from host cell
GO:1902187
IEA
Genome Projectnegative regulation of viral release from host cell

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003700
TAS
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016874
IEA
Genome Projectligase activity
GO:0016881
IEA
Genome Projectacid-amino acid ligase activity
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:1904264
IMP
Genome Projectubiquitin protein ligase activity involved in ERAD pathway

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001841Zinc finger, RING-type
IPR001870B30.2/SPRY domain
IPR003877SPRY domain
IPR003879Butyrophylin-like
IPR006574SPRY-associated
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR013320Concanavalin A-like lectin/glucanase domain
IPR017907Zinc finger, RING-type, conserved site

No MapMan annotations defined for this gene.