Gene: ENSG00000120251 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000120251
Transcript Identifier
ENST00000264426
Gene Type
Coding gene
Location
4 : 157221043-157363044 : positive

Family Information

Homologous gene family
HOM03P000932
(65 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P002420
(30 genes in 4 species)
specific family

Descriptions

gene_descr
glutamate receptor, ionotropic, AMPA 2

Identifiers

Type Value
pidENSP00000264426
HGNC4572
UniprotP42262

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007268
TAS, IEA
Genome Projectsynaptic transmission
GO:0034220
IBA
Genome Projection transmembrane transport
GO:0035235
IDA
Genome Projectionotropic glutamate receptor signaling pathway
GO:0035249
IBA
Genome Projectsynaptic transmission, glutamatergic

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
IEA
Genome Projectreceptor activity
GO:0004970
IDA
IEA
Genome Projectionotropic glutamate receptor activity
GO:0004971
ISS
TAS
Genome ProjectAMPA glutamate receptor activity
GO:0005216
IEA
Genome Projection channel activity
GO:0005234
IBA
IEA
Genome Projectextracellular-glutamate-gated ion channel activity
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
ISS
Genome Projectintegral component of plasma membrane
GO:0008021
IEA
Genome Projectsynaptic vesicle
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IBA
Genome Projectdendrite
GO:0030666
TAS
Genome Projectendocytic vesicle membrane
GO:0032281
ISS, IBA
IEA
Genome ProjectAMPA glutamate receptor complex
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IBA
IEA
Genome Projectpostsynaptic membrane
GO:0097060
IEA
Genome Projectsynaptic membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001320Ionotropic glutamate receptor
IPR001508Ionotropic glutamate receptor, metazoa
IPR001828Receptor, ligand binding region
IPR019594Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
IPR028082Periplasmic binding protein-like I

No MapMan annotations defined for this gene.