Gene: ENSG00000120129 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000120129
Transcript Identifier
ENST00000239223
Gene Type
Coding gene
Location
5 : 172768762-172770952 : negative

Family Information

Homologous gene family
HOM03P000093
(285 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P013055
(7 genes in 7 species)
specific family

Descriptions

gene_descr
dual specificity phosphatase 1

Identifiers

Type Value
pidENSP00000239223
HGNC3064
UniprotP28562

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000188
ISS
Genome Projectinactivation of MAPK activity
GO:0001706
IBA
Genome Projectendoderm formation
GO:0006470
IBA
IEA
Genome Projectprotein dephosphorylation
GO:0006979
TAS
Genome Projectresponse to oxidative stress
GO:0007049
IEA
Genome Projectcell cycle
GO:0009416
IEA
Genome Projectresponse to light stimulus
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0016311
IEA
Genome Projectdephosphorylation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032526
IEA
Genome Projectresponse to retinoic acid
GO:0032870
IEA
Genome Projectcellular response to hormone stimulus
GO:0033574
IEA
Genome Projectresponse to testosterone
GO:0035335
ISS
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0035970
ISS
Genome Projectpeptidyl-threonine dephosphorylation
GO:0042542
IEA
Genome Projectresponse to hydrogen peroxide
GO:0042981
IBA
Genome Projectregulation of apoptotic process
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043407
IDA
Genome Projectnegative regulation of MAP kinase activity
GO:0043409
ISS
Genome Projectnegative regulation of MAPK cascade
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0051447
ISS
Genome Projectnegative regulation of meiotic cell cycle
GO:0051591
IEA
Genome Projectresponse to cAMP
GO:0051592
IEA
Genome Projectresponse to calcium ion
GO:0070373
IEA
Genome Projectnegative regulation of ERK1 and ERK2 cascade
GO:0071850
ISS
Genome Projectmitotic cell cycle arrest
GO:0090266
ISS
Genome Projectregulation of mitotic cell cycle spindle assembly checkpoint
GO:2000279
IEA
Genome Projectnegative regulation of DNA biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
IEA
Genome Projectphosphoprotein phosphatase activity
GO:0004725
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0004726
TAS
Genome Projectnon-membrane spanning protein tyrosine phosphatase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008138
IBA
IEA
Genome Projectprotein tyrosine/serine/threonine phosphatase activity
GO:0008330
IEA
Genome Projectprotein tyrosine/threonine phosphatase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
IEA
Genome Projectphosphatase activity
GO:0017017
ISS
IEA
Genome ProjectMAP kinase tyrosine/serine/threonine phosphatase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000340Dual specificity phosphatase, catalytic domain
IPR000387Tyrosine specific protein phosphatases domain
IPR001763Rhodanese-like domain
IPR008343Mitogen-activated protein (MAP) kinase phosphatase
IPR016130Protein-tyrosine phosphatase, active site
IPR020417Atypical dual specificity phosphatase
IPR020422Dual specificity protein phosphatase domain
IPR024950Dual specificity phosphatase
IPR029021Protein-tyrosine phosphatase-like

No MapMan annotations defined for this gene.