Gene: ENSG00000119689 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000119689
Transcript Identifier
ENST00000334220
Gene Type
Coding gene
Location
14 : 74881954-74902330 : positive

Family Information

Homologous gene family
HOM03P000118
(242 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000685
(45 genes in 39 species)
specific family

Descriptions

gene_descr
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

Identifiers

Type Value
pidENSP00000335304
HGNC2911
UniprotP36957
UniprotA0A024R6C9

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006099
TAS, IEA
Genome Projecttricarboxylic acid cycle
GO:0006103
IEA
Genome Project2-oxoglutarate metabolic process
GO:0006734
IEA
Genome ProjectNADH metabolic process
GO:0008152
IEA
Genome Projectmetabolic process
GO:0006091
TAS
Genome Projectgeneration of precursor metabolites and energy
GO:0006554
TAS
Genome Projectlysine catabolic process
GO:0033512
IEA
Genome ProjectL-lysine catabolic process to acetyl-CoA via saccharopine
GO:0034641
TAS
Genome Projectcellular nitrogen compound metabolic process
GO:0044237
TAS
Genome Projectcellular metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004149
IEA
Genome Projectdihydrolipoyllysine-residue succinyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016746
IEA
Genome Projecttransferase activity, transferring acyl groups
GO:0031072
IEA
Genome Projectheat shock protein binding
GO:0051087
IEA
Genome Projectchaperone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005886
IEA
Genome Projectplasma membrane
GO:0043209
IEA
Genome Projectmyelin sheath
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0045252
IEA
Genome Projectoxoglutarate dehydrogenase complex
GO:0005634
IDA
Genome Projectnucleus
GO:0005759
TAS
Genome Projectmitochondrial matrix
GO:0016020
IDA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000089Biotin/lipoyl attachment
IPR0010782-oxoacid dehydrogenase acyltransferase, catalytic domain
IPR0030162-oxo acid dehydrogenase, lipoyl-binding site
IPR006255Dihydrolipoamide succinyltransferase
IPR011053Single hybrid motif
IPR023213Chloramphenicol acetyltransferase-like domain

No MapMan annotations defined for this gene.