Gene: ENSG00000119541 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000119541
Transcript Identifier
ENST00000238497
Gene Type
Coding gene
Location
18 : 63390975-63422259 : negative

Family Information

Homologous gene family
HOM03P000011
(1436 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000493
(49 genes in 38 species)
specific family

Descriptions

gene_descr
vacuolar protein sorting 4 homolog B (S. cerevisiae)

Identifiers

Type Value
pidENSP00000238497
HGNC10895
UniprotO75351
UniprotA0A024R2C5

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006813
IEA
Genome Projectpotassium ion transport
GO:0007032
IEA
Genome Projectendosome organization
GO:0030301
IEA
Genome Projectcholesterol transport
GO:0000920
IMP
Genome Projectcell separation after cytokinesis
GO:0006810
IEA
Genome Projecttransport
GO:0006997
IMP
Genome Projectnucleus organization
GO:0007033
IBA
Genome Projectvacuole organization
GO:0007049
IEA
Genome Projectcell cycle
GO:0007080
IMP
Genome Projectmitotic metaphase plate congression
GO:0010824
IMP
Genome Projectregulation of centrosome duplication
GO:0010971
IMP
Genome Projectpositive regulation of G2/M transition of mitotic cell cycle
GO:0015031
IEA
Genome Projectprotein transport
GO:0016032
TAS
Genome Projectviral process
GO:0016197
IDA
TAS
Genome Projectendosomal transport
GO:0019058
TAS
Genome Projectviral life cycle
GO:0019076
IMP
Genome Projectviral release from host cell
GO:0032510
IMP
Genome Projectendosome to lysosome transport via multivesicular body sorting pathway
GO:0033993
IDA
Genome Projectresponse to lipid
GO:0039702
IGI
Genome Projectviral budding via host ESCRT complex
GO:0043162
IMP
Genome Projectubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0048524
IMP
Genome Projectpositive regulation of viral process
GO:0050792
IMP
Genome Projectregulation of viral process
GO:0051261
IDA
Genome Projectprotein depolymerization
GO:0051301
IEA
Genome Projectcell division
GO:0060548
IMP
Genome Projectnegative regulation of cell death
GO:0061024
TAS
Genome Projectmembrane organization
GO:0090611
IMP
Genome Projectubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
GO:1901673
IMP
Genome Projectregulation of mitotic spindle assembly
GO:1902188
IMP
Genome Projectpositive regulation of viral release from host cell
GO:1903542
IMP
Genome Projectnegative regulation of exosomal secretion
GO:1903543
IMP
Genome Projectpositive regulation of exosomal secretion
GO:1903724
IMP
Genome Projectpositive regulation of centriole elongation
GO:1903902
IMP
Genome Projectpositive regulation of viral life cycle
GO:0031122
IBA
Genome Projectcytoplasmic microtubule organization

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016887
IDA
Genome ProjectATPase activity
GO:0042623
IDA
NAS
Genome ProjectATPase activity, coupled
GO:0042802
IDA
Genome Projectidentical protein binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0008568
IBA
Genome Projectmicrotubule-severing ATPase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000922
IDA
Genome Projectspindle pole
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005768
IDA
IEA
Genome Projectendosome
GO:0005813
IDA
Genome Projectcentrosome
GO:0005829
TAS
Genome Projectcytosol
GO:0010008
IDA
Genome Projectendosome membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0031902
IEA
Genome Projectlate endosome membrane
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0090543
IDA
Genome ProjectFlemming body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003593AAA+ ATPase domain
IPR003959ATPase, AAA-type, core
IPR003960ATPase, AAA-type, conserved site
IPR007330MIT
IPR015415Vps4 oligomerisation, C-terminal
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.