Gene: ENSG00000119048 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000119048
Transcript Identifier
ENST00000265339
Gene Type
Coding gene
Location
5 : 134371596-134390353 : positive

Family Information

Homologous gene family
HOM03P000028
(788 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000762
(44 genes in 39 species)
specific family

Descriptions

gene_descr
ubiquitin-conjugating enzyme E2B

Identifiers

Type Value
pidENSP00000265339
HGNC12473
UniprotP63146

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000209
IMP
Genome Projectprotein polyubiquitination
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0006281
IGI
TAS, IEA
Genome ProjectDNA repair
GO:0006301
IDA
NAS
Genome Projectpostreplication repair
GO:0006344
IEA
Genome Projectmaintenance of chromatin silencing
GO:0006511
IDA
NAS
Genome Projectubiquitin-dependent protein catabolic process
GO:0006513
IMP
Genome Projectprotein monoubiquitination
GO:0006974
IDA
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007283
TAS, IEA
Genome Projectspermatogenesis
GO:0007288
IEA
Genome Projectsperm axoneme assembly
GO:0009411
IGI
Genome Projectresponse to UV
GO:0010845
IEA
Genome Projectpositive regulation of reciprocal meiotic recombination
GO:0016567
IDA
IEA
Genome Projectprotein ubiquitination
GO:0019985
TAS
Genome Projecttranslesion synthesis
GO:0031056
IEA
Genome Projectregulation of histone modification
GO:0033128
IEA
Genome Projectnegative regulation of histone phosphorylation
GO:0033522
IMP
Genome Projecthistone H2A ubiquitination
GO:0042493
IDA
Genome Projectresponse to drug
GO:0042769
TAS
Genome ProjectDNA damage response, detection of DNA damage
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043161
IDA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043951
IDA
Genome Projectnegative regulation of cAMP-mediated signaling
GO:0050821
IMP
Genome Projectprotein stabilization
GO:0051026
IEA
Genome Projectchiasma assembly
GO:0051865
IDA
Genome Projectprotein autoubiquitination
GO:0060070
ISS
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0070076
IEA
Genome Projecthistone lysine demethylation
GO:0070193
IEA
Genome Projectsynaptonemal complex organization
GO:0070534
IDA
Genome Projectprotein K63-linked ubiquitination
GO:0070936
IDA
Genome Projectprotein K48-linked ubiquitination
GO:0070979
IDA
Genome Projectprotein K11-linked ubiquitination

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004842
IDA, IMP
Genome Projectubiquitin-protein transferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016874
IEA
Genome Projectligase activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0061630
IBA
Genome Projectubiquitin protein ligase activity
GO:0061631
IEA
Genome Projectubiquitin conjugating enzyme activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000785
ISS
IEA
Genome Projectchromatin
GO:0000790
IBA
IEA
Genome Projectnuclear chromatin
GO:0001741
IEA
Genome ProjectXY body
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005657
IDA
Genome Projectreplication fork
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0033503
IDA
Genome ProjectHULC complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000608Ubiquitin-conjugating enzyme E2
IPR016135Ubiquitin-conjugating enzyme/RWD-like
IPR023313Ubiquitin-conjugating enzyme, active site

No MapMan annotations defined for this gene.