Gene: ENSG00000118432 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000118432
Transcript Identifier
ENST00000428600
Gene Type
Coding gene
Location
6 : 88143856-88145274 : negative

Family Information

Homologous gene family
HOM03P003657
(26 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P071760
(2 genes in 2 species)
specific family

Descriptions

gene_descr
cannabinoid receptor 1 (brain)

Identifiers

Type Value
pidENSP00000412192
HGNC2159
UniprotP21554
UniprotS5TLS4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002866
IEA
Genome Projectpositive regulation of acute inflammatory response to antigenic stimulus
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007187
TAS
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007188
IDA
Genome Projectadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007283
IEA
Genome Projectspermatogenesis
GO:0007413
IEA
Genome Projectaxonal fasciculation
GO:0007568
IEA
Genome Projectaging
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0007611
IEA
Genome Projectlearning or memory
GO:0007613
IEA
Genome Projectmemory
GO:0010976
IEA
Genome Projectpositive regulation of neuron projection development
GO:0019216
IEA
Genome Projectregulation of lipid metabolic process
GO:0019233
IEA
Genome Projectsensory perception of pain
GO:0031622
IEA
Genome Projectpositive regulation of fever generation
GO:0031999
IEA
Genome Projectnegative regulation of fatty acid beta-oxidation
GO:0032228
IEA
Genome Projectregulation of synaptic transmission, GABAergic
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0033004
IEA
Genome Projectnegative regulation of mast cell activation
GO:0033602
IEA
Genome Projectnegative regulation of dopamine secretion
GO:0035094
IEA
Genome Projectresponse to nicotine
GO:0038171
IDA
TAS, IEA
Genome Projectcannabinoid signaling pathway
GO:0042220
IEA
Genome Projectresponse to cocaine
GO:0042593
IEA
Genome Projectglucose homeostasis
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043271
IEA
Genome Projectnegative regulation of ion transport
GO:0043278
IEA
Genome Projectresponse to morphine
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045759
IEA
Genome Projectnegative regulation of action potential
GO:0045776
IEA
Genome Projectnegative regulation of blood pressure
GO:0045777
IEA
Genome Projectpositive regulation of blood pressure
GO:0050796
IEA
Genome Projectregulation of insulin secretion
GO:0051001
IEA
Genome Projectnegative regulation of nitric-oxide synthase activity
GO:0051966
IEA
Genome Projectregulation of synaptic transmission, glutamatergic
GO:0060135
IEA
Genome Projectmaternal process involved in female pregnancy
GO:0060259
IEA
Genome Projectregulation of feeding behavior
GO:0060405
IEA
Genome Projectregulation of penile erection

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004949
IDA
TAS, IEA
Genome Projectcannabinoid receptor activity
GO:0008144
IEA
Genome Projectdrug binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030424
IEA
Genome Projectaxon
GO:0030426
IEA
Genome Projectgrowth cone
GO:0043231
IEA
Genome Projectintracellular membrane-bounded organelle
GO:0045121
IEA
Genome Projectmembrane raft

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000810Cannabinoid receptor type 1
IPR002230Cannabinoid receptor family
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.