Gene: ENSG00000118193 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000118193
Transcript Identifier
ENST00000367350
Gene Type
Coding gene
Location
1 : 200553388-200618723 : negative

Family Information

Homologous gene family
HOM03P000016
(1236 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P065785
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
kinesin family member 14

Identifiers

Type Value
pidENSP00000356319
HGNC19181
UniprotQ15058

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001558
IMP
Genome Projectregulation of cell growth
GO:0007018
IBA
IEA
Genome Projectmicrotubule-based movement
GO:0007080
IMP
Genome Projectmitotic metaphase plate congression
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0008284
IDA, IMP
Genome Projectpositive regulation of cell proliferation
GO:0010389
IMP
Genome Projectregulation of G2/M transition of mitotic cell cycle
GO:0021685
ISS
IEA
Genome Projectcerebellar granular layer structural organization
GO:0021693
ISS
IEA
Genome Projectcerebellar Purkinje cell layer structural organization
GO:0021695
ISS
IEA
Genome Projectcerebellar cortex development
GO:0021766
ISS
IEA
Genome Projecthippocampus development
GO:0021772
ISS
IEA
Genome Projectolfactory bulb development
GO:0021846
ISS
IEA
Genome Projectcell proliferation in forebrain
GO:0021987
ISS
IEA
Genome Projectcerebral cortex development
GO:0030155
IMP
Genome Projectregulation of cell adhesion
GO:0030334
IMP
Genome Projectregulation of cell migration
GO:0030705
IBA
Genome Projectcytoskeleton-dependent intracellular transport
GO:0031146
IMP
Genome ProjectSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031641
ISS
IEA
Genome Projectregulation of myelination
GO:0032147
IMP
Genome Projectactivation of protein kinase activity
GO:0032467
IMP
Genome Projectpositive regulation of cytokinesis
GO:0032487
IMP
Genome Projectregulation of Rap protein signal transduction
GO:0033624
IMP
Genome Projectnegative regulation of integrin activation
GO:0034446
IDA
Genome Projectsubstrate adhesion-dependent cell spreading
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0043161
IMP
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043523
ISS
IEA
Genome Projectregulation of neuron apoptotic process
GO:0043524
ISS
IEA
Genome Projectnegative regulation of neuron apoptotic process
GO:0045184
IDA
Genome Projectestablishment of protein localization
GO:0051301
IEA
Genome Projectcell division
GO:1903047
IMP
Genome Projectmitotic cell cycle process
GO:1903429
IEA
Genome Projectregulation of cell maturation
GO:2000045
IMP
Genome Projectregulation of G1/S transition of mitotic cell cycle
GO:0007019
ISS
Genome Projectmicrotubule depolymerization
GO:1902519
IMP
Genome Projectresponse to docetaxel trihydrate

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003777
IBA
IEA
Genome Projectmicrotubule motor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
ISS
IEA
Genome ProjectATP binding
GO:0008017
ISS
IEA
Genome Projectmicrotubule binding
GO:0008574
ISS
IEA
Genome ProjectATP-dependent microtubule motor activity, plus-end-directed
GO:0015631
ISS
IEA
Genome Projecttubulin binding
GO:0016887
ISS, IBA
Genome ProjectATPase activity
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0030165
IDA
Genome ProjectPDZ domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005819
IEA
Genome Projectspindle
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005871
IBA
IEA
Genome Projectkinesin complex
GO:0005874
IDA
IEA
Genome Projectmicrotubule
GO:0016020
IDA
Genome Projectmembrane
GO:0030496
IDA
IEA
Genome Projectmidbody
GO:0051233
IDA
Genome Projectspindle midzone
GO:0005886
IPI
Genome Projectplasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000253Forkhead-associated (FHA) domain
IPR001752Kinesin motor domain
IPR008984SMAD/FHA domain
IPR019821Kinesin motor domain, conserved site
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR027640Kinesin-like protein
IPR032405Kinesin-associated

No MapMan annotations defined for this gene.