Gene: ENSG00000118058 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000118058
Transcript Identifier
ENST00000534358
Gene Type
Coding gene
Location
11 : 118436513-118522172 : positive

Family Information

Homologous gene family
HOM03P000090
(299 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P065978
(2 genes in 2 species)
specific family

Descriptions

gene_descr
lysine (K)-specific methyltransferase 2A

Identifiers

Type Value
pidENSP00000436786
HGNC7132
UniprotQ03164

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006306
IEA
Genome ProjectDNA methylation
GO:0006325
TAS
Genome Projectchromatin organization
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
TAS
Genome Projecttranscription from RNA polymerase II promoter
GO:0006461
IDA
Genome Projectprotein complex assembly
GO:0006915
IEA
Genome Projectapoptotic process
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0009952
IEA
Genome Projectanterior/posterior pattern specification
GO:0016568
IEA
Genome Projectchromatin modification
GO:0032259
IEA
Genome Projectmethylation
GO:0032411
IMP
Genome Projectpositive regulation of transporter activity
GO:0032922
ISS
IEA
Genome Projectcircadian regulation of gene expression
GO:0035162
TAS, IEA
Genome Projectembryonic hemopoiesis
GO:0035864
IEA
Genome Projectresponse to potassium ion
GO:0043984
IMP
Genome Projecthistone H4-K16 acetylation
GO:0045893
IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048511
IEA
Genome Projectrhythmic process
GO:0051568
IDA, IMP
IEA
Genome Projecthistone H3-K4 methylation
GO:0051569
IEA
Genome Projectregulation of histone H3-K4 methylation
GO:0051571
ISS
IEA
Genome Projectpositive regulation of histone H3-K4 methylation
GO:0051899
IEA
Genome Projectmembrane depolarization
GO:0060216
IEA
Genome Projectdefinitive hemopoiesis
GO:0071440
ISS
IEA
Genome Projectregulation of histone H3-K14 acetylation
GO:0080182
IDA
Genome Projecthistone H3-K4 trimethylation
GO:2000615
ISS
IEA
Genome Projectregulation of histone H3-K9 acetylation
GO:2001040
IMP
Genome Projectpositive regulation of cellular response to drug

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001046
ISS
IEA
Genome Projectcore promoter sequence-specific DNA binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003680
NAS
Genome ProjectAT DNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
NAS
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008168
IEA
Genome Projectmethyltransferase activity
GO:0008270
IDA
IEA
Genome Projectzinc ion binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0018024
IEA
Genome Projecthistone-lysine N-methyltransferase activity
GO:0042800
IDA, IMP
IEA
Genome Projecthistone methyltransferase activity (H3-K4 specific)
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0045322
IDA
Genome Projectunmethylated CpG binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070577
IDA
Genome Projectlysine-acetylated histone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
NAS, IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
Genome Projectcytoplasm
GO:0035097
IDA
IEA
Genome Projecthistone methyltransferase complex
GO:0071339
IDA
Genome ProjectMLL1 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001214SET domain
IPR001487Bromodomain
IPR001965Zinc finger, PHD-type
IPR002857Zinc finger, CXXC-type
IPR003616Post-SET domain
IPR003888FY-rich, N-terminal
IPR003889FY-rich, C-terminal
IPR011011Zinc finger, FYVE/PHD-type
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR016569Methyltransferase, trithorax
IPR017956AT hook, DNA-binding motif
IPR019787Zinc finger, PHD-finger

No MapMan annotations defined for this gene.