Gene: ENSG00000117707 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000117707
Transcript Identifier
ENST00000435016
Gene Type
Coding gene
Location
1 : 213996536-214035834 : positive

Family Information

Homologous gene family
HOM03P013933
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P070309
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
prospero homeobox 1

Identifiers

Type Value
pidENSP00000400694
HGNC9459
UniprotQ92786

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001709
IEA
Genome Projectcell fate determination
GO:0001822
IEP
Genome Projectkidney development
GO:0001889
IEP
IEA
Genome Projectliver development
GO:0001938
IDA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0001945
IEA
Genome Projectlymph vessel development
GO:0001946
IDA
Genome Projectlymphangiogenesis
GO:0002088
IEP
Genome Projectlens development in camera-type eye
GO:0002089
IEA
Genome Projectlens morphogenesis in camera-type eye
GO:0002194
IEA
Genome Projecthepatocyte cell migration
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007420
IEP
IEA
Genome Projectbrain development
GO:0007623
IEA
Genome Projectcircadian rhythm
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0010468
IDA
Genome Projectregulation of gene expression
GO:0010595
IDA
Genome Projectpositive regulation of endothelial cell migration
GO:0021516
ISS
Genome Projectdorsal spinal cord development
GO:0021542
ISS
IEA
Genome Projectdentate gyrus development
GO:0021707
ISS
IEA
Genome Projectcerebellar granule cell differentiation
GO:0021915
ISS
Genome Projectneural tube development
GO:0030240
ISS
IEA
Genome Projectskeletal muscle thin filament assembly
GO:0030324
IEP
Genome Projectlung development
GO:0030910
ISS
Genome Projectolfactory placode formation
GO:0031016
IEP
Genome Projectpancreas development
GO:0031667
IEA
Genome Projectresponse to nutrient levels
GO:0042752
IMP
Genome Projectregulation of circadian rhythm
GO:0043049
ISS
Genome Projectotic placode formation
GO:0043433
IDA
Genome Projectnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045071
IDA
Genome Projectnegative regulation of viral genome replication
GO:0045446
IEA
Genome Projectendothelial cell differentiation
GO:0045737
IDA
Genome Projectpositive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045787
ISS
IEA
Genome Projectpositive regulation of cell cycle
GO:0045892
IDA, IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046619
ISS
IEA
Genome Projectoptic placode formation involved in camera-type eye formation
GO:0048511
IEA
Genome Projectrhythmic process
GO:0048839
IEA
Genome Projectinner ear development
GO:0048845
ISS
IEA
Genome Projectvenous blood vessel morphogenesis
GO:0055005
ISS
IEA
Genome Projectventricular cardiac myofibril assembly
GO:0055009
ISS
IEA
Genome Projectatrial cardiac muscle tissue morphogenesis
GO:0055010
ISS
IEA
Genome Projectventricular cardiac muscle tissue morphogenesis
GO:0060042
ISS
Genome Projectretina morphogenesis in camera-type eye
GO:0060059
IEP
IEA
Genome Projectembryonic retina morphogenesis in camera-type eye
GO:0060214
ISS
IEA
Genome Projectendocardium formation
GO:0060298
ISS
IEA
Genome Projectpositive regulation of sarcomere organization
GO:0060412
ISS
IEA
Genome Projectventricular septum morphogenesis
GO:0060414
ISS
IEA
Genome Projectaorta smooth muscle tissue morphogenesis
GO:0060421
ISS
IEA
Genome Projectpositive regulation of heart growth
GO:0060836
IDA
Genome Projectlymphatic endothelial cell differentiation
GO:0060849
IMP
Genome Projectregulation of transcription involved in lymphatic endothelial cell fate commitment
GO:0061114
IEA
Genome Projectbranching involved in pancreas morphogenesis
GO:0070309
IEP
IEA
Genome Projectlens fiber cell morphogenesis
GO:0070365
IEP
IEA
Genome Projecthepatocyte differentiation
GO:0070858
IMP
Genome Projectnegative regulation of bile acid biosynthetic process
GO:0072574
IEA
Genome Projecthepatocyte proliferation
GO:0090425
IEA
Genome Projectacinar cell differentiation
GO:0097150
ISS
IEA
Genome Projectneuronal stem cell population maintenance
GO:1901978
IEA
Genome Projectpositive regulation of cell cycle checkpoint
GO:2000179
ISS
IEA
Genome Projectpositive regulation of neural precursor cell proliferation
GO:2000979
ISS
IEA
Genome Projectpositive regulation of forebrain neuron differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000981
IEA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001046
ISS
IEA
Genome Projectcore promoter sequence-specific DNA binding
GO:0003677
IMP
IEA
Genome ProjectDNA binding
GO:0003700
IC
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
ISS
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003714
IDA
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016922
IPI
Genome Projectligand-dependent nuclear receptor binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0050692
IPI
Genome ProjectDBD domain binding
GO:0050693
IPI
Genome ProjectLBD domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISS
IEA
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR009057Homeodomain-like
IPR023082Homeo-prospero domain

No MapMan annotations defined for this gene.