Gene: ENSG00000117525 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000117525
Transcript Identifier
ENST00000334047
Gene Type
Coding gene
Location
1 : 94530460-94541636 : negative

Family Information

Homologous gene family
HOM03P046830
(2 genes in 2 species)
specific family

Descriptions

gene_descr
coagulation factor III (thromboplastin, tissue factor)

Identifiers

Type Value
pidENSP00000334145
HGNC3541
UniprotP13726

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001938
IDA
Genome Projectpositive regulation of endothelial cell proliferation
GO:0002541
IDA
Genome Projectactivation of plasma proteins involved in acute inflammatory response
GO:0002543
IC
Genome Projectactivation of blood coagulation via clotting cascade
GO:0006919
IDA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007568
IEA
Genome Projectaging
GO:0007596
TAS, IEA
Genome Projectblood coagulation
GO:0007598
TAS
Genome Projectblood coagulation, extrinsic pathway
GO:0007599
IEA
Genome Projecthemostasis
GO:0009266
IEA
Genome Projectresponse to temperature stimulus
GO:0009611
IEA
Genome Projectresponse to wounding
GO:0009612
IEA
Genome Projectresponse to mechanical stimulus
GO:0010641
IDA
Genome Projectpositive regulation of platelet-derived growth factor receptor signaling pathway
GO:0014911
IEA
Genome Projectpositive regulation of smooth muscle cell migration
GO:0019221
IBA
Genome Projectcytokine-mediated signaling pathway
GO:0030335
TAS
Genome Projectpositive regulation of cell migration
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0034405
IEA
Genome Projectresponse to fluid shear stress
GO:0045766
IDA
Genome Projectpositive regulation of angiogenesis
GO:0050927
IC
Genome Projectpositive regulation of positive chemotaxis
GO:0051897
IMP
Genome Projectpositive regulation of protein kinase B signaling
GO:0055098
IEA
Genome Projectresponse to low-density lipoprotein particle
GO:0070301
IEA
Genome Projectcellular response to hydrogen peroxide

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002020
IPI
IEA
Genome Projectprotease binding
GO:0004896
IBA
Genome Projectcytokine receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005543
IDA
Genome Projectphospholipid binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IBA
TAS, NAS
Genome Projectplasma membrane
GO:0009986
IDA
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
TAS, IEA
Genome Projectintegral component of membrane
GO:0031012
IDA
Genome Projectextracellular matrix
GO:0031233
IC
Genome Projectintrinsic component of external side of plasma membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001187Tissue factor
IPR003961Fibronectin type III
IPR013783Immunoglobulin-like fold
IPR015373Interferon/interleukin receptor domain
IPR016354Tissue factor/coagulation factor III
IPR030472Tissue factor, conserved site

No MapMan annotations defined for this gene.