Gene: ENSG00000117400 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000117400
Transcript Identifier
ENST00000372470
Gene Type
Coding gene
Location
1 : 43337849-43352772 : positive

Family Information

Homologous gene family
HOM03P026517
(3 genes in 2 species)
specific family

Descriptions

gene_descr
MPL proto-oncogene, thrombopoietin receptor

Identifiers

Type Value
pidENSP00000361548
HGNC7217
UniprotP40238

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007166
TAS
Genome Projectcell surface receptor signaling pathway
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008283
TAS
Genome Projectcell proliferation
GO:0019221
IEA
Genome Projectcytokine-mediated signaling pathway
GO:0030168
TAS
Genome Projectplatelet activation
GO:0032642
IEA
Genome Projectregulation of chemokine production
GO:0038163
IMP
Genome Projectthrombopoietin-mediated signaling pathway
GO:0048872
IEA
Genome Projecthomeostasis of number of cells

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004888
TAS
Genome Projecttransmembrane signaling receptor activity
GO:0004896
IEA
Genome Projectcytokine receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0038164
IMP
Genome Projectthrombopoietin receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005794
IDA
IEA
Genome ProjectGolgi apparatus
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0009986
IDA
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003528Long hematopoietin receptor, single chain, conserved site
IPR003961Fibronectin type III
IPR013783Immunoglobulin-like fold
IPR015152Growth hormone/erythropoietin receptor, ligand binding

No MapMan annotations defined for this gene.