Gene: ENSG00000117009 (Homo sapiens)

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Gene Identifier
ENSG00000117009
Transcript Identifier
ENST00000366559
Gene Type
Coding gene
Location
1 : 241532445-241592153 : positive

Family Information

Homologous gene family
HOM03P008206
(10 genes in 9 species)
specific family

Descriptions

gene_descr
kynurenine 3-monooxygenase (kynurenine 3- hydroxylase)

Identifiers

Type Value
pidENSP00000355517
HGNC6381
UniprotO15229

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006569
TAS, IEA
Genome Projecttryptophan catabolic process
GO:0009435
IEA
Genome ProjectNAD biosynthetic process
GO:0009651
IDA
Genome Projectresponse to salt stress
GO:0019363
IEA
Genome Projectpyridine nucleotide biosynthetic process
GO:0019441
IEA
Genome Projecttryptophan catabolic process to kynurenine
GO:0019674
IBA
IEA
Genome ProjectNAD metabolic process
GO:0019805
IEA
Genome Projectquinolinate biosynthetic process
GO:0034354
IEA
Genome Project'de novo' NAD biosynthetic process from tryptophan
GO:0034641
TAS
Genome Projectcellular nitrogen compound metabolic process
GO:0043420
IEA
Genome Projectanthranilate metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0044550
IBA
Genome Projectsecondary metabolite biosynthetic process
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0070189
IDA
Genome Projectkynurenine metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004497
IEA
Genome Projectmonooxygenase activity
GO:0004502
IDA
IEA
Genome Projectkynurenine 3-monooxygenase activity
GO:0016174
IDA
Genome ProjectNAD(P)H oxidase activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0050660
IDA
IEA
Genome Projectflavin adenine dinucleotide binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IBA
IEA
Genome Projectmitochondrion
GO:0005741
ISS
IEA
Genome Projectmitochondrial outer membrane
GO:0005743
IEA
Genome Projectmitochondrial inner membrane
GO:0005829
TAS
Genome Projectcytosol
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031966
IEA
Genome Projectmitochondrial membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002938FAD-binding domain
IPR023753FAD/NAD(P)-binding domain
IPR027545Kynurenine 3-monooxygenase

No MapMan annotations defined for this gene.