Gene: ENSG00000116688 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000116688
Transcript Identifier
ENST00000235329
Gene Type
Coding gene
Location
1 : 11989169-12011565 : positive

Family Information

Homologous gene family
HOM03P017055
(5 genes in 4 species)
specific family

Descriptions

gene_descr
mitofusin 2

Identifiers

Type Value
pidENSP00000235329
HGNC16877
UniprotO95140

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001825
IEA
Genome Projectblastocyst formation
GO:0006626
IDA
Genome Projectprotein targeting to mitochondrion
GO:0006914
IEA
Genome Projectautophagy
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006986
IEA
Genome Projectresponse to unfolded protein
GO:0007006
IDA
Genome Projectmitochondrial membrane organization
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008053
IMP
ISS
NAS, IEA
Genome Projectmitochondrial fusion
GO:0034497
IDA
Genome Projectprotein localization to pre-autophagosomal structure
GO:0046580
IDA
Genome Projectnegative regulation of Ras protein signal transduction
GO:0048593
IEA
Genome Projectcamera-type eye morphogenesis
GO:0048662
ISS
IEA
Genome Projectnegative regulation of smooth muscle cell proliferation
GO:0051646
IDA
Genome Projectmitochondrion localization
GO:0007050
ISS
Genome Projectcell cycle arrest

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003924
IEA
Genome ProjectGTPase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005525
IEA
Genome ProjectGTP binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005741
TAS, IEA
Genome Projectmitochondrial outer membrane
GO:0005829
ISS
Genome Projectcytosol
GO:0015630
IEA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031306
ISS
Genome Projectintrinsic component of mitochondrial outer membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR006884Fzo/mitofusin HR2 domain
IPR027089Mitofusin-2
IPR027094Mitofusin family
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR030381Dynamin-type guanine nucleotide-binding (G) domain

No MapMan annotations defined for this gene.