Gene: ENSG00000115966 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000115966
Transcript Identifier
ENST00000392544
Gene Type
Coding gene
Location
2 : 175074609-175136443 : negative

Family Information

Homologous gene family
HOM03P005950
(15 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P071487
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
activating transcription factor 2

Identifiers

Type Value
pidENSP00000376327
HGNC784
UniprotP15336

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0003151
IEA
Genome Projectoutflow tract morphogenesis
GO:0006325
TAS
Genome Projectchromatin organization
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IMP
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IC, IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IC, IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006970
IDA
Genome Projectresponse to osmotic stress
GO:0006974
IDA, IMP
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0016573
IDA
IEA
Genome Projecthistone acetylation
GO:0031573
IMP
Genome Projectintra-S DNA damage checkpoint
GO:0032915
IEA
Genome Projectpositive regulation of transforming growth factor beta2 production
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034146
TAS
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034162
TAS
Genome Projecttoll-like receptor 9 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0045087
TAS
Genome Projectinnate immune response
GO:0045444
IEA
Genome Projectfat cell differentiation
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0051090
TAS
Genome Projectregulation of sequence-specific DNA binding transcription factor activity
GO:0051091
IMP
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051403
TAS
Genome Projectstress-activated MAPK cascade
GO:0060612
IEA
Genome Projectadipose tissue development
GO:1902110
IMP
Genome Projectpositive regulation of mitochondrial membrane permeability involved in apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IMP
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980
IDA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001076
IC
Genome Projecttranscription factor activity, RNA polymerase II transcription factor binding
GO:0001077
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001102
IPI
Genome ProjectRNA polymerase II activating transcription factor binding
GO:0001158
IDA
Genome Projectenhancer sequence-specific DNA binding
GO:0001228
IC
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IC
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003713
TAS
Genome Projecttranscription coactivator activity
GO:0004402
IDA
IEA
Genome Projecthistone acetyltransferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008140
IDA
Genome ProjectcAMP response element binding protein binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019901
IPI
Genome Projectprotein kinase binding
GO:0035497
IDA
IEA
Genome ProjectcAMP response element binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IEA
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005741
IDA
IEA
Genome Projectmitochondrial outer membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0035861
IDA
Genome Projectsite of double-strand break

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004827Basic-leucine zipper domain
IPR007087Zinc finger, C2H2
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR015880Zinc finger, C2H2-like
IPR016378Transcription factor cyclic AMP-dependent, CRE-BP1-type
IPR029836cAMP-dependent transcription factor ATF-2

No MapMan annotations defined for this gene.