Gene: ENSG00000115956 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000115956
Transcript Identifier
ENST00000234313
Gene Type
Coding gene
Location
2 : 68365352-68395816 : positive

Family Information

Homologous gene family
HOM03P012787
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P063352
(2 genes in 2 species)
specific family

Descriptions

gene_descr
pleckstrin

Identifiers

Type Value
pidENSP00000234313
HGNC9070
UniprotP08567

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002244
IEP
Genome Projecthematopoietic progenitor cell differentiation
GO:0002576
IEP
TAS
Genome Projectplatelet degranulation
GO:0006904
ISS
IEA
Genome Projectvesicle docking involved in exocytosis
GO:0007229
IDA
Genome Projectintegrin-mediated signaling pathway
GO:0007596
TAS
Genome Projectblood coagulation
GO:0010572
ISS
IEA
Genome Projectpositive regulation of platelet activation
GO:0010920
IDA
Genome Projectnegative regulation of inositol phosphate biosynthetic process
GO:0010925
IDA
Genome Projectpositive regulation of inositol-polyphosphate 5-phosphatase activity
GO:0030030
IDA
Genome Projectcell projection organization
GO:0030168
TAS
Genome Projectplatelet activation
GO:0030836
IDA
Genome Projectpositive regulation of actin filament depolymerization
GO:0030845
IDA
Genome Projectphospholipase C-inhibiting G-protein coupled receptor signaling pathway
GO:0030866
IDA
Genome Projectcortical actin cytoskeleton organization
GO:0031529
IDA
Genome Projectruffle organization
GO:0031532
IDA
Genome Projectactin cytoskeleton reorganization
GO:0032233
IDA
Genome Projectpositive regulation of actin filament bundle assembly
GO:0033625
ISS
IEA
Genome Projectpositive regulation of integrin activation
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0045744
IDA
Genome Projectnegative regulation of G-protein coupled receptor protein signaling pathway
GO:0046488
IDA
Genome Projectphosphatidylinositol metabolic process
GO:0050849
NAS
Genome Projectnegative regulation of calcium-mediated signaling
GO:0060305
IDA
Genome Projectregulation of cell diameter
GO:0070493
IDA
Genome Projectthrombin receptor signaling pathway
GO:0070527
IMP
ISS
Genome Projectplatelet aggregation
GO:0070528
ISS
IEA
Genome Projectprotein kinase C signaling
GO:0070560
ISS
IEA
Genome Projectprotein secretion by platelet

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005080
IDA
Genome Projectprotein kinase C binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0043325
IDA
Genome Projectphosphatidylinositol-3,4-bisphosphate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS
Genome Projectextracellular region
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0016020
IDA
Genome Projectmembrane
GO:0032587
IDA
Genome Projectruffle membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000591DEP domain
IPR001849Pleckstrin homology domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR011993PH domain-like

No MapMan annotations defined for this gene.