Gene: ENSG00000115353 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000115353
Transcript Identifier
ENST00000305249
Gene Type
Coding gene
Location
2 : 75049432-75198934 : negative

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P076095
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
tachykinin receptor 1

Identifiers

Type Value
pidENSP00000303522
HGNC11526
UniprotP25103

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002118
IEA
Genome Projectaggressive behavior
GO:0002526
IEA
Genome Projectacute inflammatory response
GO:0002687
IEA
Genome Projectpositive regulation of leukocyte migration
GO:0003051
IEA
Genome Projectangiotensin-mediated drinking behavior
GO:0006954
TAS
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007200
TAS
Genome Projectphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204
IEA
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007217
IDA
TAS
Genome Projecttachykinin receptor signaling pathway
GO:0007611
IEA
Genome Projectlearning or memory
GO:0007616
IEA
Genome Projectlong-term memory
GO:0008217
IEA
Genome Projectregulation of blood pressure
GO:0008306
IEA
Genome Projectassociative learning
GO:0009408
IEA
Genome Projectresponse to heat
GO:0009582
TAS
Genome Projectdetection of abiotic stimulus
GO:0009725
IEA
Genome Projectresponse to hormone
GO:0010193
IEA
Genome Projectresponse to ozone
GO:0010634
IEA
Genome Projectpositive regulation of epithelial cell migration
GO:0010996
IEA
Genome Projectresponse to auditory stimulus
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0014910
IEA
Genome Projectregulation of smooth muscle cell migration
GO:0032224
IEA
Genome Projectpositive regulation of synaptic transmission, cholinergic
GO:0032230
IEA
Genome Projectpositive regulation of synaptic transmission, GABAergic
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032570
IEA
Genome Projectresponse to progesterone
GO:0035094
IEA
Genome Projectresponse to nicotine
GO:0035106
IEA
Genome Projectoperant conditioning
GO:0035815
IEA
Genome Projectpositive regulation of renal sodium excretion
GO:0042713
IEA
Genome Projectsperm ejaculation
GO:0042755
IEA
Genome Projecteating behavior
GO:0043117
IEA
Genome Projectpositive regulation of vascular permeability
GO:0043278
IEA
Genome Projectresponse to morphine
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045760
IEA
Genome Projectpositive regulation of action potential
GO:0045777
IEA
Genome Projectpositive regulation of blood pressure
GO:0045778
IEA
Genome Projectpositive regulation of ossification
GO:0045907
IEA
Genome Projectpositive regulation of vasoconstriction
GO:0046878
IEA
Genome Projectpositive regulation of saliva secretion
GO:0046887
IEA
Genome Projectpositive regulation of hormone secretion
GO:0048265
IEA
Genome Projectresponse to pain
GO:0048266
IEA
Genome Projectbehavioral response to pain
GO:0048660
IEA
Genome Projectregulation of smooth muscle cell proliferation
GO:0050671
IEA
Genome Projectpositive regulation of lymphocyte proliferation
GO:0050679
IEA
Genome Projectpositive regulation of epithelial cell proliferation
GO:0051496
IEA
Genome Projectpositive regulation of stress fiber assembly
GO:0051602
IEA
Genome Projectresponse to electrical stimulus
GO:0060083
IEA
Genome Projectsmooth muscle contraction involved in micturition
GO:0070472
IEA
Genome Projectregulation of uterine smooth muscle contraction
GO:0070474
IEA
Genome Projectpositive regulation of uterine smooth muscle contraction

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004995
TAS, IEA
Genome Projecttachykinin receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016496
IBA
IEA
Genome Projectsubstance P receptor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IEA
Genome Projectcytosol
GO:0005886
IDA
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0009986
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0030425
IEA
Genome Projectdendrite
GO:0044297
IEA
Genome Projectcell body
GO:0071944
IEA
Genome Projectcell periphery

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000046Neurokinin NK1 receptor
IPR000276G protein-coupled receptor, rhodopsin-like
IPR001681Neurokinin receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.