Gene: ENSG00000115266 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000115266
Transcript Identifier
ENST00000535453
Gene Type
Coding gene
Location
19 : 1453002-1470213 : positive

Family Information

Homologous gene family
HOM03P013209
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P029792
(3 genes in 2 species)
specific family

Descriptions

gene_descr
adenomatosis polyposis coli 2

Identifiers

Type Value
pidENSP00000442954
HGNC24036
UniprotO95996

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0030178
IEA
Genome Projectnegative regulation of Wnt signaling pathway
GO:0035414
IDA
Genome Projectnegative regulation of catenin import into nucleus
GO:0090090
IDA
IEA
Genome Projectnegative regulation of canonical Wnt signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
IDA
IEA
Genome Projectbeta-catenin binding
GO:0008017
IEA
Genome Projectmicrotubule binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005794
IDA
IEA
Genome ProjectGolgi apparatus
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005884
IDA
Genome Projectactin filament
GO:0005886
IEA
Genome Projectplasma membrane
GO:0015630
IDA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0016342
IDA
Genome Projectcatenin complex
GO:0031258
IDA
Genome Projectlamellipodium membrane
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm
GO:0005881
IDA
Genome Projectcytoplasmic microtubule

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000225Armadillo
IPR009223Adenomatous polyposis coli protein, cysteine-rich repeat
IPR009224SAMP
IPR009234Adenomatous polyposis coli protein basic domain
IPR011989Armadillo-like helical
IPR016024Armadillo-type fold
IPR026818Adenomatous polyposis coli (APC) family
IPR026831Adenomatous polyposis coli protein
IPR026837Adenomatous polyposis coli 2
IPR032038Adenomatous polyposis coli, N-terminal dimerisation domain

No MapMan annotations defined for this gene.