Gene: ENSG00000115263 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000115263
Transcript Identifier
ENST00000375497
Gene Type
Coding gene
Location
2 : 162143905-162149178 : negative

Family Information

Homologous gene family
HOM03P027038
(3 genes in 2 species)
specific family

Descriptions

gene_descr
glucagon

Identifiers

Type Value
pidENSP00000364647
HGNC4191
UniprotP01275

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006112
TAS
Genome Projectenergy reserve metabolic process
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007186
TAS
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007188
IBA
IEA
Genome Projectadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007631
TAS
Genome Projectfeeding behavior
GO:0008283
TAS
Genome Projectcell proliferation
GO:0010737
IBA
IEA
Genome Projectprotein kinase A signaling
GO:0010800
IEA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0030819
IEA
Genome Projectpositive regulation of cAMP biosynthetic process
GO:0032092
IEA
Genome Projectpositive regulation of protein binding
GO:0032099
IEA
Genome Projectnegative regulation of appetite
GO:0033138
IEA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0035774
IBA
IEA
Genome Projectpositive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0035948
IEA
Genome Projectpositive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0042594
IBA
Genome Projectresponse to starvation
GO:0043066
IBA
IEA
Genome Projectnegative regulation of apoptotic process
GO:0044267
TAS
Genome Projectcellular protein metabolic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045860
IEA
Genome Projectpositive regulation of protein kinase activity
GO:0050796
TAS, IEA
Genome Projectregulation of insulin secretion
GO:0051571
IEA
Genome Projectpositive regulation of histone H3-K4 methylation
GO:0070374
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071377
TAS
Genome Projectcellular response to glucagon stimulus
GO:0090280
IEA
Genome Projectpositive regulation of calcium ion import
GO:1900118
IEA
Genome Projectnegative regulation of execution phase of apoptosis
GO:2001243
IEA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
TAS
Genome Projectreceptor binding
GO:0005179
IBA
IEA
Genome Projecthormone activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0031769
IBA
IEA
Genome Projectglucagon receptor binding
GO:0042802
IPI
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS, IEA
Genome Projectextracellular region
GO:0005615
IBA
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005788
TAS
Genome Projectendoplasmic reticulum lumen
GO:0005886
TAS
Genome Projectplasma membrane
GO:0034774
TAS
Genome Projectsecretory granule lumen

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000532Glucagon/GIP/secretin/VIP
IPR015550Glucagon

No MapMan annotations defined for this gene.