Gene: ENSG00000114166 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000114166
Transcript Identifier
ENST00000263754
Gene Type
Coding gene
Location
3 : 20040478-20152525 : positive

Family Information

Homologous gene family
HOM03P000936
(64 genes in 38 species)
specific family
Orthologous gene family
ORTHO03P000991
(41 genes in 37 species)
specific family

Descriptions

gene_descr
K(lysine) acetyltransferase 2B

Identifiers

Type Value
pidENSP00000263754
HGNC8638
UniprotQ92831

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006325
TAS
Genome Projectchromatin organization
GO:0006338
IDA
TAS, NAS
Genome Projectchromatin remodeling
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006360
TAS
Genome Projecttranscription from RNA polymerase I promoter
GO:0006361
TAS
Genome Projecttranscription initiation from RNA polymerase I promoter
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006473
TAS, IEA
Genome Projectprotein acetylation
GO:0007049
IEA
Genome Projectcell cycle
GO:0007050
TAS
Genome Projectcell cycle arrest
GO:0007219
TAS
Genome ProjectNotch signaling pathway
GO:0007613
IEA
Genome Projectmemory
GO:0008285
IDA
Genome Projectnegative regulation of cell proliferation
GO:0010467
TAS
Genome Projectgene expression
GO:0010835
IDA
Genome Projectregulation of protein ADP-ribosylation
GO:0010976
IEA
Genome Projectpositive regulation of neuron projection development
GO:0016032
IEA
Genome Projectviral process
GO:0016573
IEA
Genome Projecthistone acetylation
GO:0018076
IDA
Genome ProjectN-terminal peptidyl-lysine acetylation
GO:0018393
IDA
Genome Projectinternal peptidyl-lysine acetylation
GO:0018394
IDA
Genome Projectpeptidyl-lysine acetylation
GO:0032869
IDA
Genome Projectcellular response to insulin stimulus
GO:0034599
IEA
Genome Projectcellular response to oxidative stress
GO:0035563
IEA
Genome Projectpositive regulation of chromatin binding
GO:0035948
IEA
Genome Projectpositive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0043966
IDA
Genome Projecthistone H3 acetylation
GO:0043970
IEA
Genome Projecthistone H3-K9 acetylation
GO:0045736
IEA
Genome Projectnegative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045909
IEA
Genome Projectpositive regulation of vasodilation
GO:0045944
IDA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048511
IEA
Genome Projectrhythmic process
GO:0071374
IEA
Genome Projectcellular response to parathyroid hormone stimulus
GO:0071442
IEA
Genome Projectpositive regulation of histone H3-K14 acetylation
GO:2000617
IEA
Genome Projectpositive regulation of histone H3-K9 acetylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003712
IPI
Genome Projecttranscription cofactor activity
GO:0003713
IDA
Genome Projecttranscription coactivator activity
GO:0004402
IDA, IMP
IEA
Genome Projecthistone acetyltransferase activity
GO:0004468
IDA
ISS
Genome Projectlysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0004861
ISS
IEA
Genome Projectcyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008080
IEA
Genome ProjectN-acetyltransferase activity
GO:0008134
IPI
IEA
Genome Projecttranscription factor binding
GO:0016407
IDA
Genome Projectacetyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016746
IEA
Genome Projecttransferase activity, transferring acyl groups
GO:0019901
ISS
IEA
Genome Projectprotein kinase binding
GO:0032403
IDA
Genome Projectprotein complex binding
GO:0035035
IEA
Genome Projecthistone acetyltransferase binding
GO:0042826
IPI
IEA
Genome Projecthistone deacetylase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000123
IEA
Genome Projecthistone acetyltransferase complex
GO:0000125
NAS
Genome ProjectPCAF complex
GO:0000776
IEA
Genome Projectkinetochore
GO:0000790
IEA
Genome Projectnuclear chromatin
GO:0005634
ISS
TAS, IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005671
IDA
Genome ProjectAda2/Gcn5/Ada3 transcription activator complex
GO:0005829
IEA
Genome Projectcytosol
GO:0031672
IEA
Genome ProjectA band
GO:0031674
IEA
Genome ProjectI band
GO:0042641
IEA
Genome Projectactomyosin

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000182GNAT domain
IPR001487Bromodomain
IPR009464PCAF, N-terminal
IPR016181Acyl-CoA N-acyltransferase
IPR016376Histone acetylase PCAF
IPR018359Bromodomain, conserved site

No MapMan annotations defined for this gene.