Gene: ENSG00000113749 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000113749
Transcript Identifier
ENST00000377291
Gene Type
Coding gene
Location
5 : 175683234-175685526 : positive

Family Information

Homologous gene family
HOM03P000241
(150 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P069078
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
histamine receptor H2

Identifiers

Type Value
pidENSP00000366506
HGNC5183
UniprotP25021

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001696
IEA
Genome Projectgastric acid secretion
GO:0001697
IBA
IEA
Genome Projecthistamine-induced gastric acid secretion
GO:0001698
IEA
Genome Projectgastrin-induced gastric acid secretion
GO:0001963
IBA
Genome Projectsynaptic transmission, dopaminergic
GO:0003382
IEA
Genome Projectepithelial cell morphogenesis
GO:0006955
TAS
Genome Projectimmune response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007187
TAS
Genome ProjectG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007191
IBA
Genome Projectadenylate cyclase-activating dopamine receptor signaling pathway
GO:0007606
IBA
Genome Projectsensory perception of chemical stimulus
GO:0007612
IBA
Genome Projectlearning
GO:0007613
IEA
Genome Projectmemory
GO:0008542
IEA
Genome Projectvisual learning
GO:0010579
IBA
Genome Projectpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0045907
IEA
Genome Projectpositive regulation of vasoconstriction
GO:0048167
IEA
Genome Projectregulation of synaptic plasticity
GO:0048565
IEA
Genome Projectdigestive tract development
GO:0048732
IEA
Genome Projectgland development
GO:0060158
IBA
Genome Projectphospholipase C-activating dopamine receptor signaling pathway
GO:1901998
IEA
Genome Projecttoxin transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IEA
Genome ProjectG-protein coupled receptor activity
GO:0004969
TAS, IEA
Genome Projecthistamine receptor activity
GO:0001588
IBA
Genome Projectdopamine neurotransmitter receptor activity, coupled via Gs
GO:0035240
IBA
Genome Projectdopamine binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
TAS, IEA
Genome Projectplasma membrane
GO:0005887
TAS
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR000503Histamine H2 receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.