Gene: ENSG00000113522 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000113522
Transcript Identifier
ENST00000378823
Gene Type
Coding gene
Location
5 : 132557325-132642364 : positive

Family Information

Homologous gene family
HOM03P001713
(46 genes in 38 species)
specific family
Orthologous gene family
ORTHO03P001054
(41 genes in 36 species)
specific family

Descriptions

gene_descr
RAD50 homolog (S. cerevisiae)

Identifiers

Type Value
pidENSP00000368100
HGNC9816
UniprotQ92878

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000019
IDA
Genome Projectregulation of mitotic recombination
GO:0000723
TAS, IEA
Genome Projecttelomere maintenance
GO:0000724
TAS
Genome Projectdouble-strand break repair via homologous recombination
GO:0006281
IDA
TAS, IEA
Genome ProjectDNA repair
GO:0006302
IMP
TAS
Genome Projectdouble-strand break repair
GO:0006310
IDA
Genome ProjectDNA recombination
GO:0006974
IDA
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007004
IDA
Genome Projecttelomere maintenance via telomerase
GO:0007049
IEA
Genome Projectcell cycle
GO:0007131
TAS
Genome Projectreciprocal meiotic recombination
GO:0007346
IEA
Genome Projectregulation of mitotic cell cycle
GO:0016032
IEA
Genome Projectviral process
GO:0031954
IDA
Genome Projectpositive regulation of protein autophosphorylation
GO:0032508
IMP
Genome ProjectDNA duplex unwinding
GO:0033674
IDA
Genome Projectpositive regulation of kinase activity
GO:0051276
IEA
Genome Projectchromosome organization
GO:0051321
IEA
Genome Projectmeiotic cell cycle
GO:0070192
IEA
Genome Projectchromosome organization involved in meiotic cell cycle
GO:0090305
IDA
Genome Projectnucleic acid phosphodiester bond hydrolysis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003677
IDA
Genome ProjectDNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016887
IEA
Genome ProjectATPase activity
GO:0030674
IDA
Genome Projectprotein binding, bridging
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0000014
IDA
Genome Projectsingle-stranded DNA endodeoxyribonuclease activity
GO:0004003
IMP
Genome ProjectATP-dependent DNA helicase activity
GO:0008408
IDA
Genome Project3'-5' exonuclease activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000781
IEA
Genome Projectchromosome, telomeric region
GO:0000784
IDA
Genome Projectnuclear chromosome, telomeric region
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005694
IEA
Genome Projectchromosome
GO:0016020
IDA
Genome Projectmembrane
GO:0030870
IDA
IEA
Genome ProjectMre11 complex
GO:0035861
IDA
Genome Projectsite of double-strand break
GO:0045120
IEA
Genome Projectpronucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004584DNA repair protein Rad50, eukaryotes
IPR013134RAD50, zinc hook
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.