Gene: ENSG00000113360 (Homo sapiens)

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Gene Identifier
ENSG00000113360
Transcript Identifier
ENST00000344624
Gene Type
Coding gene
Location
5 : 31401432-31529059 : negative

Family Information

Homologous gene family
HOM03P007631
(11 genes in 10 species)
specific family

Descriptions

gene_descr
drosha, ribonuclease type III

Identifiers

Type Value
pidENSP00000339845
HGNC17904
UniprotQ9NRR4

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006396
IEA
Genome ProjectRNA processing
GO:0010467
TAS
Genome Projectgene expression
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0010586
IEA
Genome ProjectmiRNA metabolic process
GO:0010628
IEA
Genome Projectpositive regulation of gene expression
GO:0016075
IEA
Genome ProjectrRNA catabolic process
GO:0030422
IBA
Genome Projectproduction of siRNA involved in RNA interference
GO:0031047
IEA
Genome Projectgene silencing by RNA
GO:0031053
IDA, IMP
Genome Projectprimary miRNA processing
GO:0031054
IBA
IEA
Genome Projectpre-miRNA processing
GO:0042254
IEA
Genome Projectribosome biogenesis
GO:0050829
IDA
Genome Projectdefense response to Gram-negative bacterium
GO:0050830
IDA
Genome Projectdefense response to Gram-positive bacterium
GO:0090305
IEA
Genome Projectnucleic acid phosphodiester bond hydrolysis
GO:0090501
IDA
IEA
Genome ProjectRNA phosphodiester bond hydrolysis
GO:0090502
IDA
IEA
Genome ProjectRNA phosphodiester bond hydrolysis, endonucleolytic
GO:2000628
IEA
Genome Projectregulation of miRNA metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001530
IDA
Genome Projectlipopolysaccharide binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003725
IBA
Genome Projectdouble-stranded RNA binding
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0004521
IEA
Genome Projectendoribonuclease activity
GO:0004525
IDA
IEA
Genome Projectribonuclease III activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0070878
NAS
Genome Projectprimary miRNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005730
IEA
Genome Projectnucleolus
GO:0070877
IDA
Genome Projectmicroprocessor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000999Ribonuclease III domain
IPR011907Ribonuclease III
IPR014720Double-stranded RNA-binding domain

No MapMan annotations defined for this gene.