Gene: ENSG00000112658 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000112658
Transcript Identifier
ENST00000265354
Gene Type
Coding gene
Location
6 : 43171657-43179190 : positive

Family Information

Homologous gene family
HOM03P032197
(2 genes in 2 species)
specific family

Descriptions

gene_descr
serum response factor (c-fos serum response element- binding transcription factor)

Identifiers

Type Value
pidENSP00000265354
HGNC11291
UniprotP11831
UniprotA0A024RD16

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001569
IEA
Genome Projectpatterning of blood vessels
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001707
IEA
Genome Projectmesoderm formation
GO:0001764
IEA
Genome Projectneuron migration
GO:0001947
ISS
IEA
Genome Projectheart looping
GO:0002011
IEA
Genome Projectmorphogenesis of an epithelial sheet
GO:0002521
IEA
Genome Projectleukocyte differentiation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007015
IEA
Genome Projectactin filament organization
GO:0007160
IEA
Genome Projectcell-matrix adhesion
GO:0007369
IEA
Genome Projectgastrulation
GO:0007507
ISS
IEA
Genome Projectheart development
GO:0007616
IEA
Genome Projectlong-term memory
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0008306
IEA
Genome Projectassociative learning
GO:0010669
IEA
Genome Projectepithelial structure maintenance
GO:0016337
IEA
Genome Projectsingle organismal cell-cell adhesion
GO:0021766
IEA
Genome Projecthippocampus development
GO:0022028
IEA
Genome Projecttangential migration from the subventricular zone to the olfactory bulb
GO:0030036
IEA
Genome Projectactin cytoskeleton organization
GO:0030038
IEA
Genome Projectcontractile actin filament bundle assembly
GO:0030155
IEA
Genome Projectregulation of cell adhesion
GO:0030168
IEA
Genome Projectplatelet activation
GO:0030220
IEA
Genome Projectplatelet formation
GO:0030336
IEA
Genome Projectnegative regulation of cell migration
GO:0031175
IEA
Genome Projectneuron projection development
GO:0033561
IEA
Genome Projectregulation of water loss via skin
GO:0035855
IEA
Genome Projectmegakaryocyte development
GO:0035912
IEA
Genome Projectdorsal aorta morphogenesis
GO:0042789
ISS
IEA
Genome ProjectmRNA transcription from RNA polymerase II promoter
GO:0043149
IEA
Genome Projectstress fiber assembly
GO:0043589
IEA
Genome Projectskin morphogenesis
GO:0045059
IEA
Genome Projectpositive thymic T cell selection
GO:0045214
IEA
Genome Projectsarcomere organization
GO:0045773
IEA
Genome Projectpositive regulation of axon extension
GO:0045893
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046016
IEA
Genome Projectpositive regulation of transcription by glucose
GO:0046716
ISS
IEA
Genome Projectmuscle cell cellular homeostasis
GO:0048589
IEA
Genome Projectdevelopmental growth
GO:0048821
IEA
Genome Projecterythrocyte development
GO:0051491
IEA
Genome Projectpositive regulation of filopodium assembly
GO:0055003
IEA
Genome Projectcardiac myofibril assembly
GO:0060218
IEA
Genome Projecthematopoietic stem cell differentiation
GO:0060292
IEA
Genome Projectlong term synaptic depression
GO:0060347
IEA
Genome Projectheart trabecula formation
GO:0060425
IEA
Genome Projectlung morphogenesis
GO:0060532
IEA
Genome Projectbronchus cartilage development
GO:0060534
IEA
Genome Projecttrachea cartilage development
GO:0060947
IEA
Genome Projectcardiac vascular smooth muscle cell differentiation
GO:0061029
IEA
Genome Projecteyelid development in camera-type eye
GO:0061145
IEA
Genome Projectlung smooth muscle development
GO:0070830
IEA
Genome Projectbicellular tight junction assembly
GO:0071333
IEA
Genome Projectcellular response to glucose stimulus
GO:0090009
IEA
Genome Projectprimitive streak formation
GO:0090136
IEA
Genome Projectepithelial cell-cell adhesion
GO:0001666
IEP
Genome Projectresponse to hypoxia
GO:0001829
IDA
Genome Projecttrophectodermal cell differentiation
GO:0002042
IMP
Genome Projectcell migration involved in sprouting angiogenesis
GO:0003257
IGI
Genome Projectpositive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0009636
TAS
Genome Projectresponse to toxic substance
GO:0009725
IDA
Genome Projectresponse to hormone
GO:0010735
IDA
Genome Projectpositive regulation of transcription via serum response element binding
GO:0034097
IMP
NAS
Genome Projectresponse to cytokine
GO:0045597
IDA
Genome Projectpositive regulation of cell differentiation
GO:0045987
IDA
Genome Projectpositive regulation of smooth muscle contraction
GO:0048666
TAS
Genome Projectneuron development
GO:0051091
IDA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051150
TAS
Genome Projectregulation of smooth muscle cell differentiation
GO:0060055
TAS
Genome Projectangiogenesis involved in wound healing
GO:0060261
IDA
Genome Projectpositive regulation of transcription initiation from RNA polymerase II promoter
GO:0090398
IMP
Genome Projectcellular senescence
GO:1900222
IMP
Genome Projectnegative regulation of beta-amyloid clearance

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
ISS
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076
IEA
Genome Projecttranscription factor activity, RNA polymerase II transcription factor binding
GO:0001228
ISS
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IEA
Genome Projectchromatin binding
GO:0003705
IEA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0031490
IEA
Genome Projectchromatin DNA binding
GO:0042826
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0046983
IEA
Genome Projectprotein dimerization activity
GO:0001077
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0010736
IDA
Genome Projectserum response element binding
GO:0042803
IPI
Genome Projectprotein homodimerization activity
GO:0000983
IMP
Genome Projecttranscription factor activity, RNA polymerase II core promoter sequence-specific

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IEA
Genome Projectnuclear chromatin
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005737
TAS, IEA
Genome Projectcytoplasm
GO:0005654
TAS
Genome Projectnucleoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002100Transcription factor, MADS-box

No MapMan annotations defined for this gene.