Gene: ENSG00000112115 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000112115
Transcript Identifier
ENST00000340057
Gene Type
Coding gene
Location
6 : 52186432-52189292 : positive

Family Information

Homologous gene family
HOM03P024506
(3 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
interleukin 17A

Identifiers

Type Value
pidENSP00000344192
HGNC5981
UniprotQ16552

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006486
TAS
Genome Projectprotein glycosylation
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006954
IEA
Genome Projectinflammatory response
GO:0006955
TAS
Genome Projectimmune response
GO:0007267
TAS
Genome Projectcell-cell signaling
GO:0008219
TAS
Genome Projectcell death
GO:0010940
IEA
Genome Projectpositive regulation of necrotic cell death
GO:0032747
IDA
Genome Projectpositive regulation of interleukin-23 production
GO:0043200
IEA
Genome Projectresponse to amino acid
GO:0045672
IDA
Genome Projectpositive regulation of osteoclast differentiation
GO:0045944
IDA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0071347
IEA
Genome Projectcellular response to interleukin-1
GO:0071385
IEA
Genome Projectcellular response to glucocorticoid stimulus
GO:0072537
IDA
Genome Projectfibroblast activation
GO:1900017
IEA
Genome Projectpositive regulation of cytokine production involved in inflammatory response

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
TAS, IEA
Genome Projectcytokine activity
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
TAS, IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0009897
IEA
Genome Projectexternal side of plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR010345Interleukin-17 family
IPR020440Interleukin-17, chordata
IPR029034Cystine-knot cytokine

No MapMan annotations defined for this gene.