Gene: ENSG00000111266 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000111266
Transcript Identifier
ENST00000298573
Gene Type
Coding gene
Location
12 : 12476833-12521098 : negative

Family Information

Homologous gene family
HOM03P000093
(285 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P044946
(2 genes in 1 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
dual specificity phosphatase 16

Identifiers

Type Value
pidENSP00000298573
HGNC17909
UniprotQ9BY84
UniprotA0A024RAR2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000188
TAS, IEA
Genome Projectinactivation of MAPK activity
GO:0006470
IBA
IEA
Genome Projectprotein dephosphorylation
GO:0016311
TAS, IEA
Genome Projectdephosphorylation
GO:0035335
IEA
Genome Projectpeptidyl-tyrosine dephosphorylation
GO:0043409
IEA
Genome Projectnegative regulation of MAPK cascade
GO:0045204
TAS
Genome ProjectMAPK export from nucleus
GO:0045209
TAS
Genome ProjectMAPK phosphatase export from nucleus, leptomycin B sensitive

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
TAS, IEA
Genome Projectphosphoprotein phosphatase activity
GO:0004725
IEA
Genome Projectprotein tyrosine phosphatase activity
GO:0008138
IBA
IEA
Genome Projectprotein tyrosine/serine/threonine phosphatase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016791
IEA
Genome Projectphosphatase activity
GO:0017017
IEA
Genome ProjectMAP kinase tyrosine/serine/threonine phosphatase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
TAS, IEA
Genome Projectnucleus
GO:0005654
IDA
Genome Projectnucleoplasm
GO:0005737
TAS, IEA
Genome Projectcytoplasm
GO:0005829
IEA
Genome Projectcytosol
GO:0016023
IEA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0031410
IEA
Genome Projectcytoplasmic vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000340Dual specificity phosphatase, catalytic domain
IPR000387Tyrosine specific protein phosphatases domain
IPR001763Rhodanese-like domain
IPR008343Mitogen-activated protein (MAP) kinase phosphatase
IPR016130Protein-tyrosine phosphatase, active site
IPR020422Dual specificity protein phosphatase domain
IPR024950Dual specificity phosphatase
IPR029021Protein-tyrosine phosphatase-like

No MapMan annotations defined for this gene.