Gene: ENSG00000110911 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000110911
Transcript Identifier
ENST00000547688
Gene Type
Coding gene
Location
12 : 50988325-51028225 : negative

Family Information

Homologous gene family
HOM03P000475
(100 genes in 35 species)
specific family
Orthologous gene family
ORTHO03P000788
(43 genes in 29 species)
specific family

Descriptions

gene_descr
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2

Identifiers

Type Value
pidENSP00000449200
HGNC10908
UniprotP49281

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000041
IEA
Genome Projecttransition metal ion transport
GO:0001666
IEP
IEA
Genome Projectresponse to hypoxia
GO:0003032
IEP
Genome Projectdetection of oxygen
GO:0006778
IEA
Genome Projectporphyrin-containing compound metabolic process
GO:0006779
IEA
Genome Projectporphyrin-containing compound biosynthetic process
GO:0006783
IEA
Genome Projectheme biosynthetic process
GO:0006810
IEA
Genome Projecttransport
GO:0006811
IEA
Genome Projection transport
GO:0006824
IDA
IEA
Genome Projectcobalt ion transport
GO:0006825
IDA
Genome Projectcopper ion transport
GO:0006826
IEA
Genome Projectiron ion transport
GO:0006828
IDA
Genome Projectmanganese ion transport
GO:0006878
IEA
Genome Projectcellular copper ion homeostasis
GO:0006879
TAS
Genome Projectcellular iron ion homeostasis
GO:0006919
IDA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007611
IEA
Genome Projectlearning or memory
GO:0010039
IEP
IEA
Genome Projectresponse to iron ion
GO:0010042
IEA
Genome Projectresponse to manganese ion
GO:0010288
IEA
Genome Projectresponse to lead ion
GO:0015675
IDA
Genome Projectnickel cation transport
GO:0015676
IDA
Genome Projectvanadium ion transport
GO:0015684
IDA
Genome Projectferrous iron transport
GO:0015692
IDA
Genome Projectlead ion transport
GO:0015992
IEA
Genome Projectproton transport
GO:0033572
NAS
Genome Projecttransferrin transport
GO:0034599
IDA
Genome Projectcellular response to oxidative stress
GO:0034755
IEA
Genome Projectiron ion transmembrane transport
GO:0035434
IDA
IEA
Genome Projectcopper ion transmembrane transport
GO:0035444
IDA
IEA
Genome Projectnickel cation transmembrane transport
GO:0046686
IEA
Genome Projectresponse to cadmium ion
GO:0048813
IEA
Genome Projectdendrite morphogenesis
GO:0048821
IEA
Genome Projecterythrocyte development
GO:0055072
IEA
Genome Projectiron ion homeostasis
GO:0055085
TAS
Genome Projecttransmembrane transport
GO:0060586
IMP
Genome Projectmulticellular organismal iron ion homeostasis
GO:0070574
IDA
Genome Projectcadmium ion transmembrane transport
GO:0070627
IDA
Genome Projectferrous iron import
GO:0071281
IEA
Genome Projectcellular response to iron ion
GO:0071356
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0071421
IDA
IEA
Genome Projectmanganese ion transmembrane transport
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0071577
IDA
Genome Projectzinc II ion transmembrane transport
GO:0098655
IGI
Genome Projectcation transmembrane transport
GO:1902600
IEA
Genome Projecthydrogen ion transmembrane transport
GO:1902861
IEA
Genome Projectcopper ion import into cell
GO:1903874
IDA, IMP
IEA
Genome Projectferrous iron transmembrane transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005215
IEA
Genome Projecttransporter activity
GO:0005375
IDA
IEA
Genome Projectcopper ion transmembrane transporter activity
GO:0005381
IEA
Genome Projectiron ion transmembrane transporter activity
GO:0005384
IDA
IEA
Genome Projectmanganese ion transmembrane transporter activity
GO:0005385
IDA
Genome Projectzinc ion transmembrane transporter activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0005507
IEA
Genome Projectcopper ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0015078
IEA
Genome Projecthydrogen ion transmembrane transporter activity
GO:0015086
IDA
IEA
Genome Projectcadmium ion transmembrane transporter activity
GO:0015087
IDA
IEA
Genome Projectcobalt ion transmembrane transporter activity
GO:0015093
IDA
IEA
Genome Projectferrous iron transmembrane transporter activity
GO:0015094
IDA
IEA
Genome Projectlead ion transmembrane transporter activity
GO:0015099
IDA
IEA
Genome Projectnickel cation transmembrane transporter activity
GO:0015100
IDA
Genome Projectvanadium ion transmembrane transporter activity
GO:0015295
IDA
Genome Projectsolute:proton symporter activity
GO:0015639
IMP
Genome Projectferrous iron uptake transmembrane transporter activity
GO:0016151
IEA
Genome Projectnickel cation binding
GO:0022890
IGI
Genome Projectinorganic cation transmembrane transporter activity
GO:0030145
IEA
Genome Projectmanganese ion binding
GO:0033570
NAS
Genome Projecttransferrin transmembrane transporter activity
GO:0046870
IDA
IEA
Genome Projectcadmium ion binding
GO:0046915
IDA
Genome Projecttransition metal ion transmembrane transporter activity
GO:0050897
IEA
Genome Projectcobalt ion binding
GO:0015085
IDA
Genome Projectcalcium ion transmembrane transporter activity
GO:0070835
IDA
Genome Projectchromium ion transmembrane transporter activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005741
IEA
Genome Projectmitochondrial outer membrane
GO:0005764
IDA
Genome Projectlysosome
GO:0005765
IDA
IEA
Genome Projectlysosomal membrane
GO:0005768
IEA
Genome Projectendosome
GO:0005769
IDA
IEA
Genome Projectearly endosome
GO:0005770
IDA
Genome Projectlate endosome
GO:0005773
IMP
Genome Projectvacuole
GO:0005802
IDA
Genome Projecttrans-Golgi network
GO:0005886
IDA, IMP
TAS, IEA
Genome Projectplasma membrane
GO:0005887
IDA, IMP
Genome Projectintegral component of plasma membrane
GO:0005903
IEA
Genome Projectbrush border
GO:0009986
IDA
Genome Projectcell surface
GO:0010008
IEA
Genome Projectendosome membrane
GO:0012505
IEA
Genome Projectendomembrane system
GO:0016020
IDA
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0031410
IDA
Genome Projectcytoplasmic vesicle
GO:0031902
IDA
IEA
Genome Projectlate endosome membrane
GO:0045177
IDA
IEA
Genome Projectapical part of cell
GO:0045178
IDA
Genome Projectbasal part of cell
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm
GO:0055037
IDA
Genome Projectrecycling endosome
GO:0070826
IDA
Genome Projectparaferritin complex
GO:0030904
IDA
Genome Projectretromer complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001046NRAMP family

No MapMan annotations defined for this gene.