Gene: ENSG00000110514 (Homo sapiens)

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Gene Identifier
ENSG00000110514
Transcript Identifier
ENST00000311027
Gene Type
Coding gene
Location
11 : 47273915-47329150 : positive

Family Information

Homologous gene family
HOM03P023493
(3 genes in 3 species)
specific family

Descriptions

gene_descr
MAP-kinase activating death domain

Identifiers

Type Value
pidENSP00000310933
HGNC6766
UniprotQ8WXG6

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IMP
Genome Projectactivation of MAPK activity
GO:0006915
IEA
Genome Projectapoptotic process
GO:0007166
TAS
Genome Projectcell surface receptor signaling pathway
GO:0032483
IDA
Genome Projectregulation of Rab protein signal transduction
GO:0042981
IMP
Genome Projectregulation of apoptotic process
GO:0043547
IDA, IMP
IEA
Genome Projectpositive regulation of GTPase activity
GO:0051726
IMP
Genome Projectregulation of cell cycle
GO:0097194
IMP
Genome Projectexecution phase of apoptosis
GO:1902041
IMP
Genome Projectregulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001234
IEA
Genome Projectnegative regulation of apoptotic signaling pathway
GO:2001236
IDA
Genome Projectregulation of extrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005123
TAS
Genome Projectdeath receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0017112
IDA, IMP
Genome ProjectRab guanyl-nucleotide exchange factor activity
GO:0030295
TAS
Genome Projectprotein kinase activator activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
TAS, IEA
Genome Projectcytoplasm
GO:0005886
IDA
TAS
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IDA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001194DENN domain
IPR005112dDENN domain
IPR005113uDENN domain

No MapMan annotations defined for this gene.