Gene: ENSG00000109339 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000109339
Transcript Identifier
ENST00000359221
Gene Type
Coding gene
Location
4 : 86017228-86194401 : negative

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P011492
(7 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
mitogen-activated protein kinase 10

Identifiers

Type Value
pidENSP00000352157
HGNC6872
UniprotP53779

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
TAS
Genome Projectactivation of MAPK activity
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002755
TAS
Genome ProjectMyD88-dependent toll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006468
IMP
ISS
IEA
Genome Projectprotein phosphorylation
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007254
ISS
TAS, IEA
Genome ProjectJNK cascade
GO:0007258
IEA
Genome ProjectJUN phosphorylation
GO:0009416
ISS
Genome Projectresponse to light stimulus
GO:0016310
IEA
Genome Projectphosphorylation
GO:0034134
TAS
Genome Projecttoll-like receptor 2 signaling pathway
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0034146
TAS
Genome Projecttoll-like receptor 5 signaling pathway
GO:0034162
TAS
Genome Projecttoll-like receptor 9 signaling pathway
GO:0034166
TAS
Genome Projecttoll-like receptor 10 signaling pathway
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0038095
TAS
Genome ProjectFc-epsilon receptor signaling pathway
GO:0038123
TAS
Genome Projecttoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124
TAS
Genome Projecttoll-like receptor TLR6:TLR2 signaling pathway
GO:0042752
ISS
Genome Projectregulation of circadian rhythm
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048511
IEA
Genome Projectrhythmic process
GO:0051090
TAS
Genome Projectregulation of sequence-specific DNA binding transcription factor activity
GO:0051403
TAS
Genome Projectstress-activated MAPK cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004705
ISS
TAS, IEA
Genome ProjectJUN kinase activity
GO:0004707
IEA
Genome ProjectMAP kinase activity
GO:0004708
TAS
Genome ProjectMAP kinase kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005739
ISS
IEA
Genome Projectmitochondrion
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
ISS
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0097481
IEA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003527Mitogen-activated protein (MAP) kinase, conserved site
IPR008271Serine/threonine-protein kinase, active site
IPR008351Mitogen-activated protein (MAP) kinase, JNK
IPR011009Protein kinase-like domain

No MapMan annotations defined for this gene.