Gene: ENSG00000109332 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000109332
Transcript Identifier
ENST00000357194
Gene Type
Coding gene
Location
4 : 102797415-102868744 : negative

Family Information

Homologous gene family
HOM03P000028
(788 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000179
(65 genes in 39 species)
specific family

Descriptions

gene_descr
ubiquitin-conjugating enzyme E2D 3

Identifiers

Type Value
pidENSP00000349722
HGNC12476
UniprotP61077

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
TAS
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000209
IDA
Genome Projectprotein polyubiquitination
GO:0002224
TAS
Genome Projecttoll-like receptor signaling pathway
GO:0002756
TAS
Genome ProjectMyD88-independent toll-like receptor signaling pathway
GO:0006281
IEA
Genome ProjectDNA repair
GO:0006351
TAS
Genome Projecttranscription, DNA-templated
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006464
TAS
Genome Projectcellular protein modification process
GO:0006511
TAS, IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0006513
IDA
Genome Projectprotein monoubiquitination
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006974
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007179
TAS
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0010467
TAS
Genome Projectgene expression
GO:0016567
IDA
IEA
Genome Projectprotein ubiquitination
GO:0030509
TAS
Genome ProjectBMP signaling pathway
GO:0032480
TAS
Genome Projectnegative regulation of type I interferon production
GO:0034138
TAS
Genome Projecttoll-like receptor 3 signaling pathway
GO:0034142
TAS
Genome Projecttoll-like receptor 4 signaling pathway
GO:0035666
TAS
Genome ProjectTRIF-dependent toll-like receptor signaling pathway
GO:0043161
IDA
Genome Projectproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0051865
IDA
Genome Projectprotein autoubiquitination
GO:0061418
TAS
Genome Projectregulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070936
IDA
Genome Projectprotein K48-linked ubiquitination
GO:0070979
IDA
Genome Projectprotein K11-linked ubiquitination
GO:0071456
TAS
Genome Projectcellular response to hypoxia
GO:1903955
IMP
Genome Projectpositive regulation of protein targeting to mitochondrion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004842
IDA
TAS
Genome Projectubiquitin-protein transferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016874
IEA
Genome Projectligase activity
GO:0061631
IDA
Genome Projectubiquitin conjugating enzyme activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005654
TAS
Genome Projectnucleoplasm
GO:0005768
IEA
Genome Projectendosome
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0010008
IEA
Genome Projectendosome membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000608Ubiquitin-conjugating enzyme E2
IPR016135Ubiquitin-conjugating enzyme/RWD-like
IPR023313Ubiquitin-conjugating enzyme, active site

No MapMan annotations defined for this gene.