Gene: ENSG00000109132 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000109132
Transcript Identifier
ENST00000226382
Gene Type
Coding gene
Location
4 : 41745807-41748610 : negative

Family Information

Homologous gene family
HOM03P000330
(126 genes in 5 species)
specific family
Orthologous gene family
ORTHO03P068376
(2 genes in 2 species)
specific family

Descriptions

gene_descr
paired-like homeobox 2b

Identifiers

Type Value
pidENSP00000226382
HGNC9143
UniprotQ99453

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001764
ISS
IEA
Genome Projectneuron migration
GO:0002087
ISS
IEA
Genome Projectregulation of respiratory gaseous exchange by neurological system process
GO:0003357
ISS
IC, IEA
Genome Projectnoradrenergic neuron differentiation
GO:0003358
ISS
IEA
Genome Projectnoradrenergic neuron development
GO:0003360
IEP
Genome Projectbrainstem development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0010001
ISS
IEA
Genome Projectglial cell differentiation
GO:0010468
ISS
IEA
Genome Projectregulation of gene expression
GO:0010971
ISS
Genome Projectpositive regulation of G2/M transition of mitotic cell cycle
GO:0021533
ISS
IEA
Genome Projectcell differentiation in hindbrain
GO:0021723
ISS
IEA
Genome Projectmedullary reticular formation development
GO:0021934
ISS
IEA
Genome Projecthindbrain tangential cell migration
GO:0030182
IEA
Genome Projectneuron differentiation
GO:0035914
IEA
Genome Projectskeletal muscle cell differentiation
GO:0045665
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045666
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0045944
IDA, IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048468
IEA
Genome Projectcell development
GO:0048483
IMP
Genome Projectautonomic nervous system development
GO:0048484
IEP
IEA
Genome Projectenteric nervous system development
GO:0048485
ISS
IEA
Genome Projectsympathetic nervous system development
GO:0048486
ISS
IEA
Genome Projectparasympathetic nervous system development
GO:0048839
ISS
IEA
Genome Projectinner ear development
GO:0048894
ISS
IEA
Genome Projectefferent axon development in a lateral line nerve
GO:0060541
ISS
IEA
Genome Projectrespiratory system development
GO:0061452
ISS
IEA
Genome Projectretrotrapezoid nucleus neuron differentiation
GO:0061549
ISS
IEA
Genome Projectsympathetic ganglion development
GO:0071157
ISS
Genome Projectnegative regulation of cell cycle arrest
GO:0071542
ISS
IC, IEA
Genome Projectdopaminergic neuron differentiation
GO:0071773
ISS
IEA
Genome Projectcellular response to BMP stimulus
GO:1901166
ISS
IEA
Genome Projectneural crest cell migration involved in autonomic nervous system development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978
IDA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IEA
Genome Projectnucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001356Homeobox domain
IPR009057Homeodomain-like
IPR017970Homeobox, conserved site

No MapMan annotations defined for this gene.