Gene: ENSG00000109072 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000109072
Transcript Identifier
ENST00000226218
Gene Type
Coding gene
Location
17 : 28367369-28370203 : negative

Family Information

Homologous gene family
HOM03P039113
(2 genes in 1 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
vitronectin

Identifiers

Type Value
pidENSP00000226218
HGNC12724
UniprotP04004
UniprotD9ZGG2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006898
IEA
Genome Projectreceptor-mediated endocytosis
GO:0006955
TAS, IEA
Genome Projectimmune response
GO:0010811
IEA
Genome Projectpositive regulation of cell-substrate adhesion
GO:0030198
TAS, IEA
Genome Projectextracellular matrix organization
GO:0048709
IEA
Genome Projectoligodendrocyte differentiation
GO:0007155
TAS, IEA
Genome Projectcell adhesion
GO:0007160
IDA
Genome Projectcell-matrix adhesion
GO:0010951
IDA
Genome Projectnegative regulation of endopeptidase activity
GO:0014911
IDA
Genome Projectpositive regulation of smooth muscle cell migration
GO:0030195
IC
Genome Projectnegative regulation of blood coagulation
GO:0030449
TAS
Genome Projectregulation of complement activation
GO:0030949
TAS
Genome Projectpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032092
IDA
Genome Projectpositive regulation of protein binding
GO:0033627
IDA
Genome Projectcell adhesion mediated by integrin
GO:0035987
IDA
Genome Projectendodermal cell differentiation
GO:0045087
TAS
Genome Projectinnate immune response
GO:0048260
IDA
Genome Projectpositive regulation of receptor-mediated endocytosis
GO:0050731
IDA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0061302
IDA
Genome Projectsmooth muscle cell-matrix adhesion
GO:0090303
IC
Genome Projectpositive regulation of wound healing

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005044
IEA
Genome Projectscavenger receptor activity
GO:0030247
IEA
Genome Projectpolysaccharide binding
GO:0050840
IEA
Genome Projectextracellular matrix binding
GO:0005178
IDA, IPI
Genome Projectintegrin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008201
IEA
Genome Projectheparin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005578
IEA
Genome Projectproteinaceous extracellular matrix
GO:0005576
TAS, NAS, IEA
Genome Projectextracellular region
GO:0005615
IDA
TAS, IEA
Genome Projectextracellular space
GO:0031012
IDA
ISS
Genome Projectextracellular matrix
GO:0070062
IDA
Genome Projectextracellular exosome
GO:0071062
TAS
Genome Projectalphav-beta3 integrin-vitronectin complex
GO:0072562
IDA
Genome Projectblood microparticle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000585Hemopexin-like domain
IPR001212Somatomedin B domain
IPR018486Hemopexin, conserved site
IPR018487Hemopexin-like repeats
IPR020436Somatomedin B, chordata

No MapMan annotations defined for this gene.