Gene: ENSG00000108961 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000108961
Transcript Identifier
ENST00000226105
Gene Type
Coding gene
Location
17 : 8288789-8289936 : positive

Family Information

Homologous gene family
HOM03P003170
(31 genes in 30 species)
specific family

Descriptions

gene_descr
RAN guanine nucleotide release factor

Identifiers

Type Value
pidENSP00000226105
HGNC17679
UniprotQ9HD47

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002027
TAS
Genome Projectregulation of heart rate
GO:0003254
IDA, IMP
Genome Projectregulation of membrane depolarization
GO:0006810
IEA
Genome Projecttransport
GO:0006888
IMP
Genome ProjectER to Golgi vesicle-mediated transport
GO:0015031
IEA
Genome Projectprotein transport
GO:0032527
IMP
Genome Projectprotein exit from endoplasmic reticulum
GO:0042391
IDA
Genome Projectregulation of membrane potential
GO:0043547
ISS
Genome Projectpositive regulation of GTPase activity
GO:0090004
IMP
Genome Projectpositive regulation of establishment of protein localization to plasma membrane
GO:1900825
TAS
Genome Projectregulation of membrane depolarization during cardiac muscle cell action potential
GO:1902305
IDA, IMP
Genome Projectregulation of sodium ion transmembrane transport
GO:2000010
IDA, IMP
Genome Projectpositive regulation of protein localization to cell surface
GO:2000649
IDA, IMP
Genome Projectregulation of sodium ion transmembrane transporter activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
ISS
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005087
ISS
IEA
Genome ProjectRan guanyl-nucleotide exchange factor activity
GO:0008536
IPI
ISS
Genome ProjectRan GTPase binding
GO:0008565
IMP
Genome Projectprotein transporter activity
GO:0017080
IDA, IMP
Genome Projectsodium channel regulator activity
GO:0044325
IPI
Genome Projection channel binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
ISS
Genome Projectnucleoplasm
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005791
IDA
Genome Projectrough endoplasmic reticulum
GO:0005886
IC
Genome Projectplasma membrane
GO:0005901
IDA
Genome Projectcaveola
GO:0014704
ISS
IEA
Genome Projectintercalated disc

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007681Ran-interacting Mog1 protein
IPR016123Mog1/PsbP, alpha/beta/alpha sandwich

No MapMan annotations defined for this gene.