Gene: ENSG00000108953 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000108953
Transcript Identifier
ENST00000264335
Gene Type
Coding gene
Location
17 : 1345447-1400110 : negative

Family Information

Homologous gene family
HOM03P000289
(137 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000127
(75 genes in 39 species)
specific family

Descriptions

gene_descr
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

Identifiers

Type Value
pidENSP00000264335
HGNC12851
UniprotP62258
UniprotV9HW98

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000086
TAS
Genome ProjectG2/M transition of mitotic cell cycle
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0001764
IEA
Genome Projectneuron migration
GO:0003064
NAS
Genome Projectregulation of heart rate by hormone
GO:0006367
TAS
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006605
IEA
Genome Projectprotein targeting
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006996
TAS
Genome Projectorganelle organization
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0010467
TAS
Genome Projectgene expression
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0016032
IEA
Genome Projectviral process
GO:0021762
IEP
Genome Projectsubstantia nigra development
GO:0021766
IEA
Genome Projecthippocampus development
GO:0021987
IEA
Genome Projectcerebral cortex development
GO:0034605
TAS
Genome Projectcellular response to heat
GO:0035308
IEA
Genome Projectnegative regulation of protein dephosphorylation
GO:0035329
TAS
Genome Projecthippo signaling
GO:0035556
TAS
Genome Projectintracellular signal transduction
GO:0043281
TAS
Genome Projectregulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048011
TAS
Genome Projectneurotrophin TRK receptor signaling pathway
GO:0060306
IDA
Genome Projectregulation of membrane repolarization
GO:0061024
TAS
Genome Projectmembrane organization
GO:0086013
IC
Genome Projectmembrane repolarization during cardiac muscle cell action potential
GO:0086091
IC
Genome Projectregulation of heart rate by cardiac conduction
GO:0097190
TAS
Genome Projectapoptotic signaling pathway
GO:0097193
TAS
Genome Projectintrinsic apoptotic signaling pathway
GO:1900034
TAS
Genome Projectregulation of cellular response to heat
GO:1900740
TAS
Genome Projectpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901016
IDA
Genome Projectregulation of potassium ion transmembrane transporter activity
GO:1902309
IDA
Genome Projectnegative regulation of peptidyl-serine dephosphorylation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0015459
IDA
Genome Projectpotassium channel regulator activity
GO:0019899
IPI
IEA
Genome Projectenzyme binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0023026
IDA
Genome ProjectMHC class II protein complex binding
GO:0031625
IPI
Genome Projectubiquitin protein ligase binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0042826
IPI
Genome Projecthistone deacetylase binding
GO:0044325
IPI
Genome Projection channel binding
GO:0044822
IDA
Genome Projectpoly(A) RNA binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity
GO:0050815
IPI
Genome Projectphosphoserine binding
GO:0051219
IPI
Genome Projectphosphoprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005739
IEA
Genome Projectmitochondrion
GO:0005829
TAS
Genome Projectcytosol
GO:0005871
IEA
Genome Projectkinesin complex
GO:0005925
IDA
Genome Projectfocal adhesion
GO:0016020
IDA
Genome Projectmembrane
GO:0030424
IEA
Genome Projectaxon
GO:0030659
TAS
Genome Projectcytoplasmic vesicle membrane
GO:0042470
IEA
Genome Projectmelanosome
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR00030814-3-3 protein
IPR02340914-3-3 protein, conserved site
IPR02341014-3-3 domain

No MapMan annotations defined for this gene.