Gene: ENSG00000108700 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000108700
Transcript Identifier
ENST00000394620
Gene Type
Coding gene
Location
17 : 34319502-34320907 : positive

Family Information

Homologous gene family
HOM03P003119
(31 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P024700
(4 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
chemokine (C-C motif) ligand 8

Identifiers

Type Value
pidENSP00000378118
HGNC10635
UniprotP80075

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002548
IBA
Genome Projectmonocyte chemotaxis
GO:0002687
IEA
Genome Projectpositive regulation of leukocyte migration
GO:0006468
IDA
Genome Projectprotein phosphorylation
GO:0006816
IDA
Genome Projectcalcium ion transport
GO:0006874
IDA
Genome Projectcellular calcium ion homeostasis
GO:0006887
IDA
Genome Projectexocytosis
GO:0006935
TAS, IEA
Genome Projectchemotaxis
GO:0006954
IBA
IEA
Genome Projectinflammatory response
GO:0006955
IEA
Genome Projectimmune response
GO:0007165
TAS
Genome Projectsignal transduction
GO:0007186
IBA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007267
IDA
Genome Projectcell-cell signaling
GO:0009615
TAS
Genome Projectresponse to virus
GO:0030593
IBA
Genome Projectneutrophil chemotaxis
GO:0043547
IBA
Genome Projectpositive regulation of GTPase activity
GO:0048245
IBA
Genome Projecteosinophil chemotaxis
GO:0048247
IBA
Genome Projectlymphocyte chemotaxis
GO:0070098
IBA
Genome Projectchemokine-mediated signaling pathway
GO:0070374
IBA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070664
IEA
Genome Projectnegative regulation of leukocyte proliferation
GO:0071346
IBA
Genome Projectcellular response to interferon-gamma
GO:0071347
IBA
Genome Projectcellular response to interleukin-1
GO:0071356
IBA
Genome Projectcellular response to tumor necrosis factor

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004672
IDA
Genome Projectprotein kinase activity
GO:0005125
IEA
Genome Projectcytokine activity
GO:0008009
TAS, IEA
Genome Projectchemokine activity
GO:0008201
IEA
Genome Projectheparin binding
GO:0016004
IDA
Genome Projectphospholipase activator activity
GO:0048020
IBA
Genome ProjectCCR chemokine receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IBA
IEA
Genome Projectextracellular space
GO:0005623
IDA
Genome Projectcell

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000827CC chemokine, conserved site
IPR001811Chemokine interleukin-8-like domain

No MapMan annotations defined for this gene.