Gene: ENSG00000108344 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000108344
Transcript Identifier
ENST00000264639
Gene Type
Coding gene
Location
17 : 39980971-39997581 : positive

Family Information

Homologous gene family
HOM03P001705
(46 genes in 39 species)
specific family

Descriptions

gene_descr
proteasome (prosome, macropain) 26S subunit, non- ATPase, 3

Identifiers

Type Value
pidENSP00000264639
HGNC9560
UniprotO43242

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000082
TAS
Genome ProjectG1/S transition of mitotic cell cycle
GO:0000209
TAS
Genome Projectprotein polyubiquitination
GO:0000278
TAS
Genome Projectmitotic cell cycle
GO:0002223
TAS
Genome Projectstimulatory C-type lectin receptor signaling pathway
GO:0002474
TAS
Genome Projectantigen processing and presentation of peptide antigen via MHC class I
GO:0002479
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0006511
IBA
Genome Projectubiquitin-dependent protein catabolic process
GO:0006521
TAS
Genome Projectregulation of cellular amino acid metabolic process
GO:0006915
TAS
Genome Projectapoptotic process
GO:0006977
TAS
Genome ProjectDNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467
TAS
Genome Projectgene expression
GO:0012501
TAS
Genome Projectprogrammed cell death
GO:0016032
TAS
Genome Projectviral process
GO:0031145
TAS
Genome Projectanaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641
TAS
Genome Projectcellular nitrogen compound metabolic process
GO:0042176
IEA
Genome Projectregulation of protein catabolic process
GO:0042590
TAS
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981
TAS
Genome Projectregulation of apoptotic process
GO:0043066
TAS
Genome Projectnegative regulation of apoptotic process
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0051436
TAS
Genome Projectnegative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437
TAS
Genome Projectpositive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
GO:0051439
TAS
Genome Projectregulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090263
TAS
Genome Projectpositive regulation of canonical Wnt signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0030234
IEA
Genome Projectenzyme regulator activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000502
IDA
TAS, IEA
Genome Projectproteasome complex
GO:0005634
IDA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005838
IEA
Genome Projectproteasome regulatory particle
GO:0008541
IBA
Genome Projectproteasome regulatory particle, lid subcomplex
GO:0016020
IDA
Genome Projectmembrane
GO:0022624
ISS
IEA
Genome Projectproteasome accessory complex
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000717Proteasome component (PCI) domain
IPR011990Tetratricopeptide-like helical domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR013143PCI/PINT associated module
IPR01358626S proteasome regulatory subunit, C-terminal

No MapMan annotations defined for this gene.