Gene: ENSG00000107954 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000107954
Transcript Identifier
ENST00000369780
Gene Type
Coding gene
Location
10 : 103494388-103590372 : positive

Family Information

Homologous gene family
HOM03P008052
(10 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P069544
(2 genes in 2 species)
specific family

Descriptions

gene_descr
neuralized E3 ubiquitin protein ligase 1

Identifiers

Type Value
pidENSP00000358795
HGNC7761
UniprotO76050

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006417
IEA
Genome Projectregulation of translation
GO:0006513
ISS
IEA
Genome Projectprotein monoubiquitination
GO:0007219
IEA
Genome ProjectNotch signaling pathway
GO:0007288
IEA
Genome Projectsperm axoneme assembly
GO:0007399
TAS
Genome Projectnervous system development
GO:0007420
IEA
Genome Projectbrain development
GO:0007519
IEA
Genome Projectskeletal muscle tissue development
GO:0007595
IEA
Genome Projectlactation
GO:0008285
IDA
Genome Projectnegative regulation of cell proliferation
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0030317
IEA
Genome Projectsperm motility
GO:0043065
IDA
Genome Projectpositive regulation of apoptotic process
GO:0045741
IEA
Genome Projectpositive regulation of epidermal growth factor-activated receptor activity
GO:0045746
IDA
Genome Projectnegative regulation of Notch signaling pathway
GO:0048170
ISS
IEA
Genome Projectpositive regulation of long-term neuronal synaptic plasticity
GO:0051491
ISS
IEA
Genome Projectpositive regulation of filopodium assembly
GO:0060999
ISS
IEA
Genome Projectpositive regulation of dendritic spine development
GO:0071230
ISS
IEA
Genome Projectcellular response to amino acid stimulus
GO:0090129
ISS
IEA
Genome Projectpositive regulation of synapse maturation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004842
ISS
IEA
Genome Projectubiquitin-protein transferase activity
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016874
IEA
Genome Projectligase activity
GO:0045183
ISS
IEA
Genome Projecttranslation factor activity, non-nucleic acid binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0061630
IEA
Genome Projectubiquitin protein ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IDA
IEA
Genome Projectplasma membrane
GO:0014069
ISS
IEA
Genome Projectpostsynaptic density
GO:0016020
IEA
Genome Projectmembrane
GO:0030054
IEA
Genome Projectcell junction
GO:0030425
IEA
Genome Projectdendrite
GO:0042995
IEA
Genome Projectcell projection
GO:0043197
ISS
IEA
Genome Projectdendritic spine
GO:0043204
ISS
IEA
Genome Projectperikaryon
GO:0045202
IEA
Genome Projectsynapse
GO:0045211
IEA
Genome Projectpostsynaptic membrane
GO:0048471
IEA
Genome Projectperinuclear region of cytoplasm
GO:0097440
ISS
IEA
Genome Projectapical dendrite

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR006573NEUZ domain
IPR013083Zinc finger, RING/FYVE/PHD-type

No MapMan annotations defined for this gene.