Gene: ENSG00000107611 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000107611
Transcript Identifier
ENST00000377833
Gene Type
Coding gene
Location
10 : 16824975-17129765 : negative

Family Information

Homologous gene family
HOM03P000563
(89 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P024488
(4 genes in 3 species)
specific family

Descriptions

gene_descr
cubilin (intrinsic factor-cobalamin receptor)

Identifiers

Type Value
pidENSP00000367064
HGNC2548
UniprotO60494

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001894
NAS
Genome Projecttissue homeostasis
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006766
TAS
Genome Projectvitamin metabolic process
GO:0006767
TAS
Genome Projectwater-soluble vitamin metabolic process
GO:0006810
IEA
Genome Projecttransport
GO:0006897
IEA
Genome Projectendocytosis
GO:0006898
NAS, IEA
Genome Projectreceptor-mediated endocytosis
GO:0008202
TAS, IEA
Genome Projectsteroid metabolic process
GO:0008203
IEA
Genome Projectcholesterol metabolic process
GO:0009235
TAS
Genome Projectcobalamin metabolic process
GO:0015031
IEA
Genome Projectprotein transport
GO:0015889
TAS
Genome Projectcobalamin transport
GO:0042157
TAS
Genome Projectlipoprotein metabolic process
GO:0042359
TAS
Genome Projectvitamin D metabolic process
GO:0042953
IEA
Genome Projectlipoprotein transport
GO:0044281
TAS
Genome Projectsmall molecule metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004872
TAS, IEA
Genome Projectreceptor activity
GO:0005215
TAS
Genome Projecttransporter activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0031419
IEA
Genome Projectcobalamin binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005764
IEA
Genome Projectlysosome
GO:0005765
IEA
Genome Projectlysosomal membrane
GO:0005768
IEA
Genome Projectendosome
GO:0005783
IEA
Genome Projectendoplasmic reticulum
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
TAS
Genome Projectplasma membrane
GO:0005903
IEA
Genome Projectbrush border
GO:0005905
IEA
Genome Projectcoated pit
GO:0010008
TAS, IEA
Genome Projectendosome membrane
GO:0016020
TAS, IEA
Genome Projectmembrane
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0030139
IDA
Genome Projectendocytic vesicle
GO:0031232
NAS
Genome Projectextrinsic component of external side of plasma membrane
GO:0031526
NAS
Genome Projectbrush border membrane
GO:0043202
TAS
Genome Projectlysosomal lumen
GO:0045177
IEA
Genome Projectapical part of cell
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000152EGF-type aspartate/asparagine hydroxylation site
IPR000742EGF-like domain
IPR000859CUB domain
IPR001881EGF-like calcium-binding domain
IPR009030Growth factor receptor cysteine-rich domain
IPR013032EGF-like, conserved site
IPR018097EGF-like calcium-binding, conserved site
IPR024731EGF domain
IPR028876Cubilin

No MapMan annotations defined for this gene.