Gene: ENSG00000107485 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000107485
Transcript Identifier
ENST00000379328
Gene Type
Coding gene
Location
10 : 8055656-8074023 : positive

Family Information

Homologous gene family
HOM03P002506
(37 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P072337
(2 genes in 2 species)
specific family

Descriptions

gene_descr
GATA binding protein 3

Identifiers

Type Value
pidENSP00000368632
HGNC4172
UniprotP23771

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000902
IEA
Genome Projectcell morphogenesis
GO:0001701
IEA
Genome Projectin utero embryonic development
GO:0001709
ISS
IEA
Genome Projectcell fate determination
GO:0001764
IEA
Genome Projectneuron migration
GO:0001775
IEA
Genome Projectcell activation
GO:0001806
IEA
Genome Projecttype IV hypersensitivity
GO:0001819
IEA
Genome Projectpositive regulation of cytokine production
GO:0001822
IMP
Genome Projectkidney development
GO:0001823
ISS
IEA
Genome Projectmesonephros development
GO:0002088
IEA
Genome Projectlens development in camera-type eye
GO:0002376
IEA
Genome Projectimmune system process
GO:0002572
IEA
Genome Projectpro-T cell differentiation
GO:0003180
ISS
IEA
Genome Projectaortic valve morphogenesis
GO:0003215
ISS
IEA
Genome Projectcardiac right ventricle morphogenesis
GO:0003281
ISS
IEA
Genome Projectventricular septum development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
TAS
Genome Projecttranscription from RNA polymerase II promoter
GO:0006952
TAS
Genome Projectdefense response
GO:0006959
IEA
Genome Projecthumoral immune response
GO:0007165
ISS
IEA
Genome Projectsignal transduction
GO:0007399
IEA
Genome Projectnervous system development
GO:0007411
IEA
Genome Projectaxon guidance
GO:0007596
TAS
Genome Projectblood coagulation
GO:0008285
ISS
IEA
Genome Projectnegative regulation of cell proliferation
GO:0008584
ISS
IEA
Genome Projectmale gonad development
GO:0009615
IEP
Genome Projectresponse to virus
GO:0009653
TAS
Genome Projectanatomical structure morphogenesis
GO:0009791
IEA
Genome Projectpost-embryonic development
GO:0009967
IMP
Genome Projectpositive regulation of signal transduction
GO:0010332
IEA
Genome Projectresponse to gamma radiation
GO:0010595
IMP
Genome Projectpositive regulation of endothelial cell migration
GO:0010629
IEA
Genome Projectnegative regulation of gene expression
GO:0010975
IEA
Genome Projectregulation of neuron projection development
GO:0014065
ISS
IEA
Genome Projectphosphatidylinositol 3-kinase signaling
GO:0030182
IEA
Genome Projectneuron differentiation
GO:0030217
IEA
Genome ProjectT cell differentiation
GO:0030218
IEA
Genome Projecterythrocyte differentiation
GO:0031929
ISS
IEA
Genome ProjectTOR signaling
GO:0032689
IEA
Genome Projectnegative regulation of interferon-gamma production
GO:0032703
IEA
Genome Projectnegative regulation of interleukin-2 production
GO:0032736
IEA
Genome Projectpositive regulation of interleukin-13 production
GO:0032753
ISS
IEA
Genome Projectpositive regulation of interleukin-4 production
GO:0032754
IEA
Genome Projectpositive regulation of interleukin-5 production
GO:0033077
IEA
Genome ProjectT cell differentiation in thymus
GO:0033600
IDA
Genome Projectnegative regulation of mammary gland epithelial cell proliferation
GO:0035162
IEA
Genome Projectembryonic hemopoiesis
GO:0035457
IEP
Genome Projectcellular response to interferon-alpha
GO:0035799
IEA
Genome Projectureter maturation
GO:0035898
IEA
Genome Projectparathyroid hormone secretion
GO:0042035
ISS
IEA
Genome Projectregulation of cytokine biosynthetic process
GO:0042421
ISS
IEA
Genome Projectnorepinephrine biosynthetic process
GO:0042472
IEA
Genome Projectinner ear morphogenesis
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043370
IEA
Genome Projectregulation of CD4-positive, alpha-beta T cell differentiation
GO:0043523
IEA
Genome Projectregulation of neuron apoptotic process
GO:0043583
IMP
Genome Projectear development
GO:0043627
IEP
Genome Projectresponse to estrogen
GO:0045061
IEA
Genome Projectthymic T cell selection
GO:0045064
IEA
Genome ProjectT-helper 2 cell differentiation
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045582
ISS
IEA
Genome Projectpositive regulation of T cell differentiation
GO:0045597
IEA
Genome Projectpositive regulation of cell differentiation
GO:0045599
IMP
Genome Projectnegative regulation of fat cell differentiation
GO:0045786
IMP
Genome Projectnegative regulation of cell cycle
GO:0045892
IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA, IMP
ISS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP
ISS
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048469
IEA
Genome Projectcell maturation
GO:0048485
ISS
IEA
Genome Projectsympathetic nervous system development
GO:0048538
IEA
Genome Projectthymus development
GO:0048568
IEA
Genome Projectembryonic organ development
GO:0048589
IEA
Genome Projectdevelopmental growth
GO:0048646
ISS
IEA
Genome Projectanatomical structure formation involved in morphogenesis
GO:0048872
IEA
Genome Projecthomeostasis of number of cells
GO:0050728
IMP
Genome Projectnegative regulation of inflammatory response
GO:0050852
ISS
IEA
Genome ProjectT cell receptor signaling pathway
GO:0051569
IEA
Genome Projectregulation of histone H3-K4 methylation
GO:0051897
IMP
Genome Projectpositive regulation of protein kinase B signaling
GO:0060017
IEA
Genome Projectparathyroid gland development
GO:0060037
ISS
IEA
Genome Projectpharyngeal system development
GO:0060065
ISS
IEA
Genome Projectuterus development
GO:0060231
IDA
Genome Projectmesenchymal to epithelial transition
GO:0060374
IEA
Genome Projectmast cell differentiation
GO:0060676
ISS
IEA
Genome Projectureteric bud formation
GO:0061085
IEA
Genome Projectregulation of histone H3-K27 methylation
GO:0061290
ISS
IEA
Genome Projectcanonical Wnt signaling pathway involved in metanephric kidney development
GO:0071345
IEA
Genome Projectcellular response to cytokine stimulus
GO:0071353
IEP
IEA
Genome Projectcellular response to interleukin-4
GO:0071356
IEP
Genome Projectcellular response to tumor necrosis factor
GO:0071599
IEA
Genome Projectotic vesicle development
GO:0071773
IEA
Genome Projectcellular response to BMP stimulus
GO:0072001
IEA
Genome Projectrenal system development
GO:0072107
ISS
IEA
Genome Projectpositive regulation of ureteric bud formation
GO:0072178
ISS
IEA
Genome Projectnephric duct morphogenesis
GO:0072179
ISS
IEA
Genome Projectnephric duct formation
GO:0072182
ISS
IEA
Genome Projectregulation of nephron tubule epithelial cell differentiation
GO:0072602
IEA
Genome Projectinterleukin-4 secretion
GO:0072643
IEA
Genome Projectinterferon-gamma secretion
GO:0072676
IDA
Genome Projectlymphocyte migration
GO:2000114
IEA
Genome Projectregulation of establishment of cell polarity
GO:2000146
IMP
Genome Projectnegative regulation of cell motility
GO:2000352
IMP
Genome Projectnegative regulation of endothelial cell apoptotic process
GO:2000607
ISS
IEA
Genome Projectnegative regulation of cell proliferation involved in mesonephros development
GO:2000611
IMP
Genome Projectpositive regulation of thyroid hormone generation
GO:2000664
IDA
Genome Projectpositive regulation of interleukin-5 secretion
GO:2000667
IDA, IMP
Genome Projectpositive regulation of interleukin-13 secretion
GO:2000679
IMP
Genome Projectpositive regulation of transcription regulatory region DNA binding
GO:2000683
IMP
Genome Projectregulation of cellular response to X-ray
GO:2000703
ISS
IEA
Genome Projectnegative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
GO:2000734
ISS
IEA
Genome Projectnegative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000976
IDA
IEA
Genome Projecttranscription regulatory region sequence-specific DNA binding
GO:0000977
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000979
IEA
Genome ProjectRNA polymerase II core promoter sequence-specific DNA binding
GO:0000987
IDA
Genome Projectcore promoter proximal region sequence-specific DNA binding
GO:0001046
IDA
Genome Projectcore promoter sequence-specific DNA binding
GO:0001071
IDA, IMP
Genome Projectnucleic acid binding transcription factor activity
GO:0001077
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001078
IMP
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001158
IEA
Genome Projectenhancer sequence-specific DNA binding
GO:0003677
TAS, IEA
Genome ProjectDNA binding
GO:0003700
TAS, IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003713
IDA
Genome Projecttranscription coactivator activity
GO:0005134
IEA
Genome Projectinterleukin-2 receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
Genome Projecttranscription factor binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
Genome Projecttranscription regulatory region DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046983
IEA
Genome Projectprotein dimerization activity
GO:0070888
IDA
Genome ProjectE-box binding
GO:0071837
IPI
Genome ProjectHMG box domain binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
IDA
Genome Projectnuclear chromatin
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
IDA
TAS
Genome Projectnucleoplasm
GO:0005730
IDA
Genome Projectnucleolus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000679Zinc finger, GATA-type
IPR013088Zinc finger, NHR/GATA-type
IPR016374Transcription factor, GATA-2/3
IPR029521Transcription factor GATA-3

No MapMan annotations defined for this gene.