Gene: ENSG00000107404 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000107404
Transcript Identifier
ENST00000378888
Gene Type
Coding gene
Location
1 : 1336142-1349065 : negative

Family Information

Homologous gene family
HOM03P015491
(5 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P068256
(2 genes in 2 species)
specific family

Descriptions

gene_descr
dishevelled segment polarity protein 1

Identifiers

Type Value
pidENSP00000368166
HGNC3084
UniprotO14640

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001505
ISS
IEA
Genome Projectregulation of neurotransmitter levels
GO:0001932
IEA
Genome Projectregulation of protein phosphorylation
GO:0001933
IEA
Genome Projectnegative regulation of protein phosphorylation
GO:0001934
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006469
IDA
Genome Projectnegative regulation of protein kinase activity
GO:0007269
ISS
IEA
Genome Projectneurotransmitter secretion
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007409
IEA
Genome Projectaxonogenesis
GO:0007411
IEA
Genome Projectaxon guidance
GO:0007528
ISS
IEA
Genome Projectneuromuscular junction development
GO:0010976
IEA
Genome Projectpositive regulation of neuron projection development
GO:0016055
IEA
Genome ProjectWnt signaling pathway
GO:0021915
IEP
Genome Projectneural tube development
GO:0022007
IEA
Genome Projectconvergent extension involved in neural plate elongation
GO:0030177
IDA
Genome Projectpositive regulation of Wnt signaling pathway
GO:0031122
IEA
Genome Projectcytoplasmic microtubule organization
GO:0032091
IDA
Genome Projectnegative regulation of protein binding
GO:0032436
IMP
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034504
IMP
Genome Projectprotein localization to nucleus
GO:0035176
IEA
Genome Projectsocial behavior
GO:0035372
IEA
Genome Projectprotein localization to microtubule
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0043113
ISS
IEA
Genome Projectreceptor clustering
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0048668
IEA
Genome Projectcollateral sprouting
GO:0048675
IEA
Genome Projectaxon extension
GO:0048813
ISS
IEA
Genome Projectdendrite morphogenesis
GO:0050808
ISS
IEA
Genome Projectsynapse organization
GO:0060029
IEA
Genome Projectconvergent extension involved in organogenesis
GO:0060070
IDA
Genome Projectcanonical Wnt signaling pathway
GO:0060071
IDA
Genome ProjectWnt signaling pathway, planar cell polarity pathway
GO:0060134
IEA
Genome Projectprepulse inhibition
GO:0071340
IEA
Genome Projectskeletal muscle acetylcholine-gated channel clustering
GO:0090090
TAS
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0090103
IEA
Genome Projectcochlea morphogenesis
GO:0090179
IBA
IEA
Genome Projectplanar cell polarity pathway involved in neural tube closure
GO:0090263
TAS, IEA
Genome Projectpositive regulation of canonical Wnt signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005109
IPI
Genome Projectfrizzled binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019901
IPI
IEA
Genome Projectprotein kinase binding
GO:0042802
IPI
Genome Projectidentical protein binding
GO:0048365
IEA
Genome ProjectRac GTPase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IBA
TAS, IEA
Genome Projectcytosol
GO:0005874
IEA
Genome Projectmicrotubule
GO:0005886
IEA
Genome Projectplasma membrane
GO:0015630
IEA
Genome Projectmicrotubule cytoskeleton
GO:0016020
IEA
Genome Projectmembrane
GO:0016023
ISS
IEA
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0030136
IEA
Genome Projectclathrin-coated vesicle
GO:0030424
IEA
Genome Projectaxon
GO:0030425
IEA
Genome Projectdendrite
GO:0030426
IEA
Genome Projectgrowth cone
GO:0031410
IDA
IEA
Genome Projectcytoplasmic vesicle
GO:0043025
IEA
Genome Projectneuronal cell body
GO:0045202
ISS
IEA
Genome Projectsynapse
GO:0016328
IDA
Genome Projectlateral plasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000591DEP domain
IPR001158DIX domain
IPR001478PDZ domain
IPR003351Dishevelled protein domain
IPR008339Dishevelled family
IPR008340Dishevelled-1
IPR011991Winged helix-turn-helix DNA-binding domain
IPR015506Dishevelled-related protein
IPR024580Dishevelled C-terminal
IPR029071Ubiquitin-related domain

No MapMan annotations defined for this gene.