Gene: ENSG00000106299 (Homo sapiens)

Overview top

Gene Identifier
ENSG00000106299
Transcript Identifier
ENST00000223023
Gene Type
Coding gene
Location
7 : 123684519-123748734 : negative

Family Information

Homologous gene family
HOM03P007790
(11 genes in 8 species)
specific family
Orthologous gene family
ORTHO03P063324
(2 genes in 2 species)
specific family

Descriptions

gene_descr
Wiskott-Aldrich syndrome-like

Identifiers

Type Value
pidENSP00000223023
HGNC12735
UniprotO00401

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006461
TAS
Genome Projectprotein complex assembly
GO:0006900
ISS
Genome Projectmembrane budding
GO:0006928
TAS
Genome Projectmovement of cell or subcellular component
GO:0007015
IEA
Genome Projectactin filament organization
GO:0007049
IEA
Genome Projectcell cycle
GO:0007067
IEA
Genome Projectmitotic nuclear division
GO:0007264
TAS
Genome Projectsmall GTPase mediated signal transduction
GO:0007411
TAS
Genome Projectaxon guidance
GO:0008154
TAS
Genome Projectactin polymerization or depolymerization
GO:0009617
IEA
Genome Projectresponse to bacterium
GO:0016050
ISS
Genome Projectvesicle organization
GO:0030036
IEA
Genome Projectactin cytoskeleton organization
GO:0030050
ISS
Genome Projectvesicle transport along actin filament
GO:0032880
IEA
Genome Projectregulation of protein localization
GO:0034629
IEA
Genome Projectcellular protein complex localization
GO:0038096
TAS
Genome ProjectFc-gamma receptor signaling pathway involved in phagocytosis
GO:0044281
TAS
Genome Projectsmall molecule metabolic process
GO:0045087
TAS
Genome Projectinnate immune response
GO:0046209
TAS
Genome Projectnitric oxide metabolic process
GO:0048013
TAS
Genome Projectephrin receptor signaling pathway
GO:0050999
TAS
Genome Projectregulation of nitric-oxide synthase activity
GO:0051301
IEA
Genome Projectcell division
GO:0051491
ISS
Genome Projectpositive regulation of filopodium assembly
GO:0051653
IEA
Genome Projectspindle localization
GO:1903526
IDA
Genome Projectnegative regulation of membrane tubulation
GO:2000370
ISS
Genome Projectpositive regulation of clathrin-mediated endocytosis
GO:2000402
IMP
Genome Projectnegative regulation of lymphocyte migration
GO:2000601
IEA
Genome Projectpositive regulation of Arp2/3 complex-mediated actin nucleation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003779
IEA
Genome Projectactin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0030695
TAS
Genome ProjectGTPase regulator activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000139
IEA
Genome ProjectGolgi membrane
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
TAS
Genome Projectplasma membrane
GO:0015629
TAS
Genome Projectactin cytoskeleton
GO:0016023
ISS
Genome Projectcytoplasmic membrane-bounded vesicle
GO:0030027
IEA
Genome Projectlamellipodium
GO:0030478
IEA
Genome Projectactin cap
GO:0030666
TAS
Genome Projectendocytic vesicle membrane
GO:0070062
IDA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000095CRIB domain
IPR000697WH1/EVH1 domain
IPR003124WH2 domain
IPR011026Wiscott-Aldrich syndrome protein, C-terminal
IPR011993PH domain-like
IPR030214Neural Wiskott-Aldrich syndrome protein

No MapMan annotations defined for this gene.